Background: The crosstalk between tumor cells and their microenvironment plays a crucial
role in the development, progression and metastasis of HCC. Hypoxia, a common feature of …

The occurrence and development of tumor depends not only on the tumor itself, but also
depends on the soil survival of tumor cells, that is the tumor microenvironment. Studies …

Introduction Solid tumours are characterised by an abnormal microenvironment that drives
tumour progression. Tumour abnormalities include matrix stiffening and solid stress …

Pancreatic cancer shows a characteristic tissue structure called desmoplasia, which consists
of dense fibrotic stroma surrounding cancer cells. Interactions between pancreatic cancer …

Pancreatic adenocarcinoma is the deadliest cancer and currently the fourth most frequent
cause of cancer-related deaths. The disease is characterized by the lack of early symptoms …

Hepatocellular carcinoma (HCC) is the third largest cause of cancer deaths worldwide. It
seems to be needed to find new ways to address the mechanisms involved in the …

Cancer is a major cause of death, and considerable research has been done to/determine
factors for its diagnosis and prognosis. As cancer tumor cells rapidly/reproduce, they use up …

One key feature of pancreatic ductal adenocarcinoma (PDAC) is a dense desmoplastic
reaction that has been recognized as playing important roles in metastasis and therapeutic …

Background: Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancer
worldwide. One key feature of PDAC is a dense desmoplastic reaction that has become …