Cellular interaction between pancreatic cancer cells and MSC as tumor microenvironment
E Kondo, K Saito - Cancer Research, 2017 - AACR
Tumor microenvironment such as neoangiogenesis, stroma and tumor immunity has
recently gained much attention because it is significantly involved in tumor progression …
recently gained much attention because it is significantly involved in tumor progression …
Lactate promotes metastasis of normoxic colorectal cancer stem cells through PGC-1α-mediated oxidative phosphorylation
S Liu, H Zhao, Y Hu, C Yan, Y Mi, X Li, D Tao… - Cell death & …, 2022 - nature.com
Uneven oxygen supply in solid tumors leads to hypoxic and normoxic regions. Hypoxic cells
exhibit increased secretion of lactate, which creates an acidic tumor microenvironment …
exhibit increased secretion of lactate, which creates an acidic tumor microenvironment …
28 Role of Microenvironment in Regulating Stem Cell and Tumor Initiating Cancer Cell Behavior and Its Potential Therapeutic
A Krtolica - … Dormancy, Quiescence, and Senescence, Volume 2 …, 2013 - books.google.com
28 Role of Microenvironment in Regulating Stem Cell and Tumor Initiating Cancer Cell Behavior
and Its Potential Therapeutic Page 317 28 Role of Microenvironment in Regulating Stem Cell and …
and Its Potential Therapeutic Page 317 28 Role of Microenvironment in Regulating Stem Cell and …
Tumor microenvironment-induced tumor cell plasticity: relationship with hypoxic stress and impact on tumor resistance
The role of tumor interaction with stromal components during carcinogenesis is crucial for
the design of efficient cancer treatment approaches. It is widely admitted that tumor hypoxic …
the design of efficient cancer treatment approaches. It is widely admitted that tumor hypoxic …
Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment
A lot of effort has been done to study how cancer cells react to low-oxygen tension, a
condition known as hypoxia. Indeed, abnormal and dysfunctional blood vessels in the tumor …
condition known as hypoxia. Indeed, abnormal and dysfunctional blood vessels in the tumor …
Hypoxic microenvironment induces EMT and upgrades stem-like properties of gastric cancer cells
J Guo, B Wang, Z Fu, J Wei… - Technology in cancer …, 2016 - journals.sagepub.com
Hypoxia microenvironment, as a major feature of solid tumors, increases tumors progression
and metastasis. To research whether hypoxia influences the epithelial–mesenchymal …
and metastasis. To research whether hypoxia influences the epithelial–mesenchymal …
The Individuality of Tumour-Stroma Interaction in Non-Small Cell Lung Cancer: Insights from Funtional and Molecular Analysis
S Gottschling, M Granzow, R Kuner, A Jauch… - …, 2009 - thieme-connect.com
Tumour-stroma interaction plays a significant role for malignant growth. Here, we analyzed
the functional and molecular sequels of interaction in a non-contact co-culture model …
the functional and molecular sequels of interaction in a non-contact co-culture model …
Abstract# 3130: Non tumorigenic side-population cells become highly tumorigenic, stem cell like cells by acquiring stemness under hypoxic microenvironment
Recent observations on the conversion of fibroblasts to induced pluripotent stem (iPS) cells
suggest that non stem cells may be converted to stem cells, and thereby acquire tumorigenic …
suggest that non stem cells may be converted to stem cells, and thereby acquire tumorigenic …
Resveratrol ameliorates the malignant progression of pancreatic cancer by inhibiting hypoxia-induced pancreatic stellate cell activation
Y Xiao, T Qin, L Sun, W Qian, J Li, W Duan… - Cell …, 2020 - journals.sagepub.com
Pancreatic cancer is characterized by a hypoxic tumor microenvironment, which is primarily
caused by massive fibrosis with pancreatic stellate cells (PSCs) as a main component. Our …
caused by massive fibrosis with pancreatic stellate cells (PSCs) as a main component. Our …
[PDF][PDF] 9th Annual EMBL-EBI PhD Seminars Day Thursday 28 April 2016 Kendrew Lecture Theatre, EBI South Building
KL Theatre - ebi.ac.uk
Mass cytometry imaging is a novel technique that allows sub-cellular resolution
measurements of the abundance of dozen proteins directly in tissues (Giesen et al.,“Highly …
measurements of the abundance of dozen proteins directly in tissues (Giesen et al.,“Highly …