Induced pluripotent stem cells (iPSC) offer the possibility to generate diverse disease-
relevant cell types, from any genetic background with the use of cellular reprogramming and …

Macrophages play important roles in many diseases. We describe a protocol and the
associated resources for the differentiation of human induced pluripotent stem cell‐derived …

Cell types differentiated from induced pluripotent stem cells (iPSCs) are frequently arrested
in their development program, more closely resembling a fetal rather than an adult …

Macrophages are present in most vertebrate tissues and comprise widely dispersed and
heterogeneous cell populations with different functions. They are key players in health and …

Human induced pluripotent stem cells (iPSCs) and macrophages derived from them are
increasingly popular tools for research into both infectious and degenerative diseases …

The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …

Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis.
Understanding of human macrophage biology has been hampered by the lack of reliable …

The observation that embryonic stem cells (ESCs) expressed reduced levels of major
histocompatibility (MHC) class I genes, no MHC class II or costimulatory molecules …

Cellular reprogramming and generation of induced pluripotent stem cells (iPSCs) from adult
cell types have enabled the creation of patient-specific stem cells for use in disease …

Macrophages derived from human induced pluripotent stem cells (iPSCs) have the potential
to enable the development of cell-based therapies for numerous disease conditions. We …