Peroxisomes are ubiquitous organelles that participate in hydrogen peroxide metabolism, ß-
oxidation of fatty acids, and other important metabolic pathways (Olsen and Harada 1995; …

Peroxisomes are organelles equipped with enzymes for lipid metabolism and hydrogen-
peroxide-based respiration. Though many details of their metabolism are understood today …

Genetic and proteomic approaches have led to the identification of 32 proteins, collectively
called peroxins, which are required for the biogenesis of peroxisomes. Some are …

Peroxisomes are organelles that perform a variety of functions, including the metabolism of
hydrogen peroxide and the oxidation of fatty acids. Peroxisomes do not possess organellar …

▪ Abstract This review summarizes the progress made in our understanding of peroxisome
biogenesis in the last few years, during which the functional roles of many of the 23 peroxins …

Peroxisomes are unique organelles whose physiological functions vary depending on the
cellular environment or metabolic and developmental state of the organism. These changes …

Proteins are targeted to the membrane and matrix of peroxisomes by distinct pathways.
Recent observations suggest a further route: a subset of peroxisomal membrane proteins …

Peroxisome biogenesis conceptually consists of the (a) formation of the peroxisomal
membrane,(b) import of proteins into the peroxisomal matrix and (c) proliferation of the …

Peroxisomes perform a wide variety of metabolic processes in eukaryotic organisms.
Mutations that affect peroxisome function or formation have profound phenotypic …

Recent results have demonstrated that the molecular mechanisms of peroxisomal
membrane biogenesis and the post-translational import of proteins into the organelle do not …