Cardamonin (CD), a naturally occurring chalcone derived from the Alpinia species, has
been shown to exert antioxidant and anti-inflammatory activity, but its role in the prevention …

Farrerol has been shown to have antioxidative potential via Nrf2 activation, which in turn is
involved in the prevention of hepatotoxicity. The purpose of the current study was to explore …

Acetaminophen (APAP) overdose is a leading cause of drug-induced acute liver failure in
clinical and hospital settings. Fisetin (FST) is a phenolic compound derived from natural …

Acetaminophen (APAP), one of the most widely used antipyretics and analgesics, principally
results in acute liver injury (ALI) in developed countries when taken overdose. Ferulic acid …

Abstract Background Cirsii Japonici Herba Carbonisata (Dajitan in Chinese) has been used
to treat liver disorders in Asian countries. Pectolinarigenin (PEC), an abundant constituent in …

Acetaminophen (APAP) overdose-induced fatal hepatotoxicity is majorly characterized by
overwhelmingly increased oxidative stress while enhanced nuclear factor-erythroid 2 …

Acetaminophen (APAP) toxicity leads to severe acute liver injury (ALI) by inducing excessive
oxidative stress, inflammatory response, and hepatocyte apoptosis. Imperatorin (IMP) is a …

Background Acetaminophen (APAP) overdose-induced acute liver failure (ALF) is mainly
resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) …

Acetaminophen (APAP) overdose-induced hepatotoxicity is the most common cause of drug-
induced liver injury worldwide, which is significantly linked to oxidative stress and sterile …

Abstract Background Tanshinone IIA (Tan), the main active component of Salvia miltiorrhiza,
has been demonstrated to have antioxidant activity. Acetaminophen (APAP), a widely used …