Background Limonin, a bioactive compound from citrus plants, exerts antioxidant activities,
however its therapeutic potential in acetaminophen (APAP)-induced hepatotoxicity remains …

Acetaminophen (APAP) overdose is the main cause of acute liver failure. Apigenin (API) is a
natural dietary flavonol with high antioxidant capacity. Herein, we investigated protection by …

Acetaminophen (APAP) overdose is a major cause of drug-induced liver injury worldwide.
Our current study was performed to assess the potential protective effects of γ-oryzanol …

Acetaminophen (APAP)-induced liver injury (AILI) is the main cause of acute liver failure in
the developed countries. The present study aimed to evaluate the therapeutic efficacy of …

Acetaminophen (APAP) is a commonly used pain and fever reliever but is also the most
frequent cause of drug-induced liver injury. The mechanism pertaining acetaminophen …

Acetaminophen (APAP)-induced hepatotoxicity is the main cause of drug-induced liver
injury. This study investigated the protection of baicalin and its aglycone baicalein against …

Overdose of acetaminophen (APAP) can cause acute liver injury that is sometimes fatal,
requiring efficient pharmacological intervention. The traditional Chinese herb Bupleurum …

Acetaminophen (APAP) is a common antipyretic and analgesic drug, but its overdose can
induce acute liver failure with lack of effective therapies. Hesperetin, a dihydrogen flavonoid …

Acetaminophen (APAP) overdose causes hepatocytes necrosis and acute liver failure.
Baicalin (BA), a major flavonoid of Scutellariae radix, has potent hepatoprotective properties …

Acetaminophen (APAP) can cause acute liver failure, but treatment options are still limited.
Kahweol is the main diterpene compound of coffee and possesses antioxidant and anti …