Diffusion and directed motion in cellular transport
We study the motion of a probe driven by microtubule-associated motors within a living
eukaryotic cell. The measured mean square displacement,< x (t) 2> of engulfed 2 and 3 μ m …
eukaryotic cell. The measured mean square displacement,< x (t) 2> of engulfed 2 and 3 μ m …
Enhanced diffusion in active intracellular transport
We show that within a living eukaryotic cell, mean square displacement of an engulfed
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …
Temporal analysis of active and passive transport in living cells
D Arcizet, B Meier, E Sackmann, JO Rädler… - Physical review letters, 2008 - APS
The cellular cytoskeleton is a fascinating active network, in which Brownian motion is
intercepted by distinct phases of active transport. We present a time-resolved statistical …
intercepted by distinct phases of active transport. We present a time-resolved statistical …
Intracellular transport by active diffusion
All substances exhibit constant random motion at the microscopic scale. This is a direct
consequence of thermal agitation, and leads to diffusion of molecules and small particles in …
consequence of thermal agitation, and leads to diffusion of molecules and small particles in …
Molecular motors pulling cargos in the viscoelastic cytosol: how power strokes beat subdiffusion
The discovery of anomalous diffusion of larger biopolymers and submicron tracers such as
endogenous granules, organelles, or virus capsids in living cells, attributed to the …
endogenous granules, organelles, or virus capsids in living cells, attributed to the …
Mechanics of single cells: rheology, time dependence, and fluctuations
G Massiera, KM Van Citters, PL Biancaniello… - Biophysical …, 2007 - cell.com
The results of mechanical measurements on single cultured epithelial cells using both
magnetic twisting cytometry (MTC) and laser tracking microrheology (LTM) are described …
magnetic twisting cytometry (MTC) and laser tracking microrheology (LTM) are described …
Local motion analysis reveals impact of the dynamic cytoskeleton on intracellular subdiffusion
Intracellular transport is a complex interplay of ballistic transport along filaments and of
diffusive motion, reliably delivering material and allowing for cell differentiation, migration …
diffusive motion, reliably delivering material and allowing for cell differentiation, migration …
Anomalous diffusion of single particles in cytoplasm
The crowded intracellular environment poses a formidable challenge to experimental and
theoretical analyses of intracellular transport mechanisms. Our measurements of single …
theoretical analyses of intracellular transport mechanisms. Our measurements of single …
Anomalous transport in the crowded world of biological cells
F Höfling, T Franosch - Reports on Progress in Physics, 2013 - iopscience.iop.org
A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …
organelles is anomalous, and a description simply based on the conventional diffusion …
How molecular motors work in the crowded environment of living cells: coexistence and efficiency of normal and anomalous transport
Recent experiments reveal both passive subdiffusion of various nanoparticles and
anomalous active transport of such particles by molecular motors in the molecularly crowded …
anomalous active transport of such particles by molecular motors in the molecularly crowded …