Current treatments for inoperable mesothelioma: indirect comparisons based on individual patient data reconstructed retrospectively from 4 trials
A Messori, S Trippoli - Journal of Chemotherapy, 2023 - Taylor & Francis
In inoperable pleural mesothelioma, pemetrexed+ cisplatin as first line is considered the
standard of care, but novel treatments have been recently proposed. Our objective was to …
standard of care, but novel treatments have been recently proposed. Our objective was to …
Systemic treatments for mesothelioma: standard and novel
HL Kindler - Current treatment options in oncology, 2008 - Springer
Opinion statement Systemic therapy is the only treatment option for the majority of
mesothelioma patients, for whom age, co-morbid medical illnesses, non-epithelial histology …
mesothelioma patients, for whom age, co-morbid medical illnesses, non-epithelial histology …
Current options for systemic therapy in mesothelioma
DM Jackman - Seminars in thoracic and cardiovascular surgery, 2009 - Elsevier
Systemic therapy options for patients with mesothelioma remain limited. Although many
conventional chemotherapeutic agents have shown modest activity in this disease, only the …
conventional chemotherapeutic agents have shown modest activity in this disease, only the …
Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label …
Background Pleural mesothelioma usually presents at an advanced, incurable stage.
Chemotherapy with platinum–pemetrexed is a standard treatment. We hypothesised that the …
Chemotherapy with platinum–pemetrexed is a standard treatment. We hypothesised that the …
Clinical trials eligibility of patients with malignant pleural mesothelioma: use of novel therapies and outcomes
Introduction Studies of bevacizumab and pembrolizumab in the treatment of malignant
pleural mesothelioma suggest anticancer efficacy; clinical trial populations are not reflective …
pleural mesothelioma suggest anticancer efficacy; clinical trial populations are not reflective …
Management of advanced pleural mesothelioma—at the crossroads
AK Nowak, A Jackson, C Sidhu - JCO Oncology Practice, 2022 - ascopubs.org
The management of pleural mesothelioma has changed with the demonstration that first-line
checkpoint blockade therapy improves survival. This review covers issues of relevance to …
checkpoint blockade therapy improves survival. This review covers issues of relevance to …
Efficacy of phase 1 trials in malignant pleural mesothelioma: description of a series of patients at a single institution
Background Malignant pleural mesothelioma (MPM) is a locally aggressive disease with a
poor prognosis. After failure of first line platinum-based chemotherapy, there is no widely …
poor prognosis. After failure of first line platinum-based chemotherapy, there is no widely …
[HTML][HTML] A real-world analysis of the use of systemic therapy in malignant pleural mesothelioma and the differential impacts on overall survival by practice pattern
Introduction Malignant pleural mesothelioma (MPM) is an aggressive malignancy that affects
older adults with frequent comorbidities, making real-world treatment decisions challenging …
older adults with frequent comorbidities, making real-world treatment decisions challenging …
Promising investigational drug candidates in phase I and phase II clinical trials for mesothelioma
A Guazzelli, E Bakker, K Tian… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Malignant mesothelioma is a rare and lethal malignancy primarily affecting the
pleura and peritoneum. Mesothelioma incidence is expected to increase worldwide and …
pleura and peritoneum. Mesothelioma incidence is expected to increase worldwide and …
A review of pharmacologic management in the treatment of mesothelioma
EP Borrelli, CG McGladrigan - Current Treatment Options in Oncology, 2021 - Springer
Opinion statement Mesothelioma is a rare and severe form of cancer that is associated with
asbestos exposure. Approximately 2500 Americans die annually from this condition with a …
asbestos exposure. Approximately 2500 Americans die annually from this condition with a …