Comparative Chronic Liver Toxicity of Benzo[a]pyrene in Two Populations of the Atlantic Killifish (Fundulus heteroclitus) with Different Exposure Histories

LP Wills, D Jung, K Koehrn, S Zhu… - Environmental …, 2010 - ehp.niehs.nih.gov
Background The Atlantic Wood Industries Superfund site on the Elizabeth River (ER) in
Portsmouth, Virginia, is contaminated with polycyclic aromatic hydrocarbons (PAHs) derived …

Effect of CYP1A inhibition on the biotransformation of benzo [a] pyrene in two populations of Fundulus heteroclitus with different exposure histories

LP Wills, S Zhu, KL Willett, RT Di Giulio - Aquatic toxicology, 2009 - Elsevier
Sediment contaminated with polycyclic aromatic hydrocarbons (PAHs) from a Superfund site
on the Elizabeth River (ER) in Portsmouth, VA, is teratogenic to embryonic killifish (Fundulus …

Biomarker sensitivity for polynuclear aromatic hydrocarbon contamination in two marine fish species collected in Galveston Bay, Texas

KL Willett, SJ McDonald, MA Steinberg… - … and Chemistry: An …, 1997 - Wiley Online Library
Abstract The Galveston Bay estuary exhibited a contamination gradient for polynuclear
aromatic hydrocarbons (PAHs) and halogenated aromatic hydrocarbons, and the …

Hepatic Responses of Juvenile Fundulus heteroclitus from Pollution-adapted and Nonadapted Populations Exposed to Elizabeth River Sediment Extract

AK Riley, M Chernick, DR Brown… - Toxicologic …, 2016 - journals.sagepub.com
Atlantic killifish (Fundulus heteroclitus) inhabiting the Atlantic Wood Industries region of the
Elizabeth River, Virginia, have passed polycyclic aromatic hydrocarbon (PAH) resistance to …

Improved flatfish health following remediation of a PAH-contaminated site in Eagle Harbor, Washington

MS Myers, BF Anulacion, BL French, WL Reichert… - Aquatic Toxicology, 2008 - Elsevier
Eagle Harbor in Puget Sound, WA became a Superfund site in 1987 due to polycyclic
aromatic hydrocarbons (PAHs) released chronically from a nearby creosoting facility. Early …

In vitro-in vivo biotransformation and phase I metabolite profiling of benzo [a] pyrene in Gulf killifish (Fundulus grandis) populations with different exposure histories

ME Franco, AJ Ramirez, KM Johanning, CW Matson… - Aquatic Toxicology, 2022 - Elsevier
Chronic exposure to pollution may lead populations to display evolutionary adaptations
associated with cellular and physiological mechanisms of defense against xenobiotics. This …

Comparative metabolism and excretion of benzo (a) pyrene in 2 species of ictalurid catfish

KL Willett, PR Gardinali, LA Lienesch… - Toxicological …, 2000 - academic.oup.com
Differential susceptibility of polycyclic aromatic hydrocarbon (PAH)-mediated liver cancer
exists in two related species of Ictalurid catfish. Two hypotheses are addressed in this study …

Effects of benzo [a] pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site

D Jung, Y Cho, LB Collins, JA Swenberg, RT Di Giulio - Aquatic toxicology, 2009 - Elsevier
Benzo [a] pyrene (BaP) is a known genotoxicant that affects both mitochondrial and nuclear
DNA (mtDNA, nDNA). Here, we examined mtDNA and nDNA damage in the Atlantic killifish …

Establishing the causal relationship between polycyclic aromatic hydrocarbon (PAH) exposure and hepatic neoplasms and neoplasia-related liver lesions in English …

MS Myers, LL Johnson, TK Collier - Human and Ecological Risk …, 2003 - Taylor & Francis
For almost 25 years our laboratory has studied the impact of PAHs and related industrial
contaminants on benthic fish, following an interdisciplinary approach involving chemical …

In vitro metabolism andin vivo binding of benzo(a)pyrene in the California killifish (Fundulus parvipinnis) and speckled sanddab (Citharicthys stigmaeous)

E von Hofe, HW Puffer - Archives of environmental contamination and …, 1986 - Springer
Aquatic species in the nearshore environment are exposed to potentially carcinogenic and
toxic hydrocarbon pollutants. The pathogenic activity of many of these hydrocarbons is …