Systemic treatment and management approaches for medullary thyroid cancer

V Ernani, M Kumar, AY Chen, TK Owonikoko - Cancer Treatment Reviews, 2016 - Elsevier
Although rare, medullary thyroid cancer (MTC) exemplifies the value that ever-expanding
knowledge of molecular pathways and mechanisms brings to managing challenging …

The Evolving Treatment Landscape of Medullary Thyroid Cancer

M Laganà, V Cremaschi, A Alberti… - … Treatment Options in …, 2023 - Springer
Opinion statement Genetic assessment is crucial to address the correct treatment for
advanced medullary thyroid cancer (MTC). Multi tyrosine kinase inhibitors (mTKIs) …

New drugs for medullary thyroid cancer: new promises?

C Spitzweg, JC Morris, KC Bible - Endocrine-Related Cancer, 2016 - erc.bioscientifica.com
Medullary thyroid cancer (MTC) is a rare tumor arising from the calcitonin-producing
parafollicular C cells of the thyroid gland, occurring either sporadically or alternatively in a …

Management of hereditary medullary thyroid carcinoma

T Pappa, M Alevizaki - Endocrine, 2016 - Springer
Hereditary medullary thyroid carcinoma (MTC) represents up to one-third of MTC cases and
includes multiple endocrine neoplasia syndrome type 2A (and its variant familial MTC) and …

Update on targeted therapy in medullary thyroid cancer

C Okafor, J Hogan, M Raygada, BJ Thomas… - Frontiers in …, 2021 - frontiersin.org
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor that accounts for 2-4% of
all thyroid cancers. All inherited MTC and approximately 50% of sporadic cases are driven …

Advanced medullary thyroid cancer: pathophysiology and management

CV Ferreira, DR Siqueira, L Ceolin… - Cancer management and …, 2013 - Taylor & Francis
Medullary thyroid carcinoma (MTC) is a rare malignant tumor originating from thyroid
parafollicular C cells. This tumor accounts for 3%–4% of thyroid gland neoplasias. MTC may …

Treating medullary thyroid cancer in the age of targeted therapy

ME Cabanillas, MI Hu, C Jimenez… - … journal of endocrine …, 2014 - Taylor & Francis
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor deriving from the thyroid
parafollicular cell. Thyroidectomy continues to serve as the primary initial treatment for this …

Medullary thyroid cancer: monitoring and therapy

DW Ball - Endocrinology and metabolism clinics of North America, 2007 - Elsevier
This article summarizes the clinical features and molecular pathogenesis of medullary
thyroid cancer (MTC) and focuses on the current use of molecular, biochemical, and imaging …

Medullary thyroid cancer: therapeutic targets and molecular markers

DW Ball - Current opinion in oncology, 2007 - journals.lww.com
Medullary thyroid cancer: therapeutic targets and molecular... : Current Opinion in Oncology
Medullary thyroid cancer: therapeutic targets and molecular markers : Current Opinion in …

Article Commentary: Medullary Thyroid Cancer: An Update for Surgeons

FK Azar, SL Lee, JE Rosen - The American Surgeon, 2015 - journals.sagepub.com
Medullary thyroid carcinoma is uncommon but accounts for approximately 4 to 5 per cent of
all thyroid cancers. Although most cases are sporadic, close to one-fourth of cases result …