Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancers

SM Vorobiev, Y Janet Huang… - Protein and peptide …, 2012 - ingentaconnect.com
Human retinoblastoma binding protein 9 (RBBP9) is an interacting partner of the
retinoblastoma susceptibility protein (Rb). RBBP9 is a tumor-associated protein required for …

[PDF][PDF] The retinoblastoma binding protein 6 is a potential target for therapeutic drugs

M Ntwasa - Biotechnol. Mol. Biol. Rev, 2008 - academia.edu
The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …

RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia

DJ Shields, S Niessen, EA Murphy… - Proceedings of the …, 2010 - National Acad Sciences
Pancreatic cancer is one of the most lethal malignancies. To discover functionally relevant
modulators of pancreatic neoplasia, we performed activity-based proteomic profiling on …

[HTML][HTML] Crystal structure of human retinoblastoma binding protein 9 (RBBP9)

SM Vorobiev, M Su, J Seetharaman, YJ Huang… - Proteins, 2009 - ncbi.nlm.nih.gov
As a step towards better integrating protein three-dimensional (3D) structural information in
cancer systems biology, the Northeast Structural Genomics Consortium (NESG)(www. nesg …

Finding enzymes that are actively involved in cancer

M Bogyo - Proceedings of the National Academy of …, 2010 - National Acad Sciences
The past decade has seen re-markable advances in the fields of both proteomics and
genomics. In addition to basic technical advances that have led to an increased volume of …

Isolation and chromosomal localization of a new human retinoblastoma binding protein 2 homologue 1a (RBBP2H1A)

V Kashuba, A Protopopov, R Podowski… - European Journal of …, 2000 - nature.com
Using a NotI linking clone NR-025 as a probe, we isolated a novel putative member of the
RB binding protein family, namely a human retinoblastoma binding protein 2 homologue …

Cloning and expression of a novel retinoblastoma binding protein cDNA, RBBP10

JZ Chen, QS Yang, S Wang, XF Meng, K Ying, Y Xie… - Biochemical …, 2002 - Springer
A 2860-bp cDNA was isolated from a human fetal brain cDNA library by high throughput
cDNA sequencing, which encodes a putative protein with 186 amino acids. The putative …

cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene product

Y Sakai, M Saijo, K Coelho, T Kishino, N Niikawa… - Genomics, 1995 - Elsevier
We have previously isolated cDNA of a novel protein (RBQ-1, HGMW-approved symbol
RBBP6) that binds to the retinoblastoma gene product (pRB). Total nucleotide sequence of …

[PDF][PDF] The retinoblastoma binding protein 6 family is essential for embryonic development and carcinogenesis

M Ntwasa, E Nweke, U Cajee - Journal of Cancer Research …, 2018 - researchgate.net
Regulators of the tumour suppressor protein, p53 are promising anti-cancer drug
candidates. The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, has …

Retinoblastoma-binding protein 2 (RBP2) is frequently expressed in neuroendocrine tumors and promotes the neoplastic phenotype

EC Maggi, J Trillo-Tinoco, AP Struckhoff… - Oncogenesis, 2016 - nature.com
Neuroendocrine tumors (NETs), which can have survival rates as low as 4%, currently have
limited therapeutic interventions available highlighting the dire need for the identification of …