[HTML][HTML] A real-world analysis of the use of systemic therapy in malignant pleural mesothelioma and the differential impacts on overall survival by practice pattern

K Kerrigan, Y Jo, J Chipman, B Haaland, S Puri… - JTO Clinical and …, 2022 - Elsevier
Introduction Malignant pleural mesothelioma (MPM) is an aggressive malignancy that affects
older adults with frequent comorbidities, making real-world treatment decisions challenging …

[HTML][HTML] Comparison of survival by multimodal treatment regimen among malignant pleural mesothelioma patients in an integrated health system

KC Banks, S Ossowski, YY Hung, DS Hsu… - Clinical Lung Cancer, 2022 - Elsevier
Background Optimal therapy for malignant pleural mesothelioma (MPM) remains unclear.
We compared overall survival in patients with MPM after various multimodal treatment …

Clinical trials eligibility of patients with malignant pleural mesothelioma: use of novel therapies and outcomes

B Lau, M Boyer, JH Lee, S Kao - Clinical Lung Cancer, 2020 - Elsevier
Introduction Studies of bevacizumab and pembrolizumab in the treatment of malignant
pleural mesothelioma suggest anticancer efficacy; clinical trial populations are not reflective …

Meta-analysis of survival and development of a prognostic nomogram for malignant pleural mesothelioma treated with systemic chemotherapy

R Kotecha, R Tonse, M Rubens, H Appel, F Albrecht… - Cancers, 2021 - mdpi.com
Simple Summary Malignant pleural mesothelioma (MPM) is a rare cancer with an
aggressive disease course. For patients who are medically inoperable or surgically …

Comparison of 3 randomized clinical trials of frontline therapies for malignant pleural mesothelioma

T Meirson, F Pentimalli, F Cerza, G Baglio… - JAMA Network …, 2022 - jamanetwork.com
Importance Some recently proposed frontline therapies for malignant pleural mesothelioma
(MPM) are very costly, yet their impact on quality of life and overall survival of these patients …

[HTML][HTML] A multicentre randomised phase III trial comparing pembrolizumab versus single-agent chemotherapy for advanced pre-treated malignant pleural …

S Popat, A Curioni-Fontecedro, U Dafni, R Shah… - Annals of …, 2020 - Elsevier
Background Malignant pleural mesothelioma (MPM) is an aggressive malignancy
characterised by limited treatment options and a poor prognosis. At relapse after platinum …

Salvage therapy for relapsed malignant pleural mesothelioma: A systematic review and network meta-analysis

YC Tsai, HL Chen, TH Lee, HM Chang, KL Wu… - Cancers, 2021 - mdpi.com
Simple Summary Malignant pleural mesothelioma (MPM) is an aggressive cancer with
limited therapeutic options. Pemetrexed plus platinum is a standard first-line therapy, but …

Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label …

Q Chu, F Perrone, L Greillier, W Tu, MC Piccirillo… - The Lancet, 2023 - thelancet.com
Background Pleural mesothelioma usually presents at an advanced, incurable stage.
Chemotherapy with platinum–pemetrexed is a standard treatment. We hypothesised that the …

Efficacy of chemotherapy for malignant pleural mesothelioma according to histology in a real-world cohort

S Cedres, JD Assaf, P Iranzo, A Callejo, N Pardo… - Scientific Reports, 2021 - nature.com
CheckMate 743 trial demonstrated survival benefit of immunotherapy in first line in MPM with
some differences in the efficacy of chemotherapy according to histology. The objective of this …

Pemetrexed in combination with cisplatin versus carboplatin as first-line therapy in patients with advanced-stage malignant pleural mesothelioma (MPM): A systematic …

SA Srour, JA Stoner - 2016 - ascopubs.org
8554 Background: Pemtrexed/cisplatin (PCisp) remains the standard frontline treatment for
advanced-stage MPM. However, a majority of patients are older and too fragile to tolerate …