Stemona alkaloids contain family members with diverse structural scaffolds. Many of them
feature a γ-lactam ring embedded in their characteristic 5–7–5 fused tricyclic core. Herein a …

In recent years, researches on the total syntheses of Stemona alkaloids with different 5/7
bicyclic systems have attracted increasing attention, and the development momentum in this …

Matrine is a traditional Chinese medicine and botanical pesticide with broad biological
activities, including pharmacological and agricultural activities. In present work, two matrine …

Five new matrine-type alkaloid dimers, alopecuroides A–E, were isolated from the aerial
parts of Sophora alopecuroides. Alopecuroides A and B represent the first dimeric matrine …

Three new matrine-type alkaloids,(+)-5α-hydroxyoxysophocarpine (1),(−)-12β-
hydroxyoxysophocarpine (2), and (+)-5α-hydroxylemannine (3), along with 14 known …

A unified total synthesis of stemoamide-type alkaloids is reported. Our synthetic approach
features the chemoselective convergent assembly of five-membered building blocks via …

Three matrine-derived alkaloids, alopecuroidine A (1), alopecuroidine B (2a) and
alopecuroidine C (2b) were isolated from the seeds of Sophora alopecuroides. Their …

The asymmetric total syntheses of five pyrrole-type Stemona alkaloids and two
stereoisomers were accomplished, among which 3-n-butylneostemonine and …

The total synthesis of three diastereomeric matrine natural products is reported. The 8-step
synthesis commences with simple acyclic precursors, forms all 4 rings of the tetracyclic …

As The main effective monomer of the traditional Chinese medicine Sophora flavescens Ait,
matrine has a broad scope of pharmacological activities such as anti-tumor, anti …