Average life expectancy is continuously rising in all developed countries, leading to an ever-
increasing elderly population. Of the many functions of the body affected by the complex …

Vaccines are powerful public health tools that have been of tremendous benefit in protecting
vulnerable populations worldwide from many pathogens. However, vaccine-preventable …

Older adults are more susceptible to viral and bacterial infection, and experience higher
incidence and severity of infectious diseases. Although vaccination is the most logical …

The immune system of the elderly is particularly susceptible to infectious diseases and
displays reduced response to vaccination. The current vaccines, designed for young and …

Successful vaccination of the elderly against important infectious pathogens that cause high
morbidity and mortality represents a growing public health priority. Building on the theme of …

The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …

The aging immune system demonstrates a reduced capacity to mount a robust immune
response (immunosenescence), thereby increasing the susceptibility to various infectious …

The increased susceptibility of the elderly to infection presents a major challenge to public
health services. An aging immune system is well documented as the cause of increased …

Prolonged life expectancy in the 20th century has been one of humankind's greatest
triumphs. However, the substantial increase in the human life span has ushered in a new …

People with advanced age have a higher susceptibility to infections and exhibit increased
mortality and morbidity as the ability of the immune system to combat infections decreases …