The aim of the present study was to investigate the role of primary afferent fibres with
polymodal nociceptors in the various pain symptoms and signs associated with post …

The hypothesis that the pain and allodynia associated with post-herpetic neuralgia (PHN) is
maintained by a combination of input from preserved primary afferent nociceptors and …

Background In postherpetic neuralgia (PHN), dorsal root ganglia neurons are damaged.
According to the proposed models, PHN pain might be associated with nociceptive …

Postherpetic neuralgia (PHN) is a common and often devastatingly painful condition. It is
also one of the most extensively investigated of the neuropathic pains. Patients with PHN …

In order to evaluate the efficacy, time-course of action and predictors of response to topical
capsaicin, 39 patients with chronic post-herpetic neuralgia (PHN), median duration 24 …

Postherpetic neuralgia (PHN) is a neuropathic pain syndrome associated with the
reactivation of varicella zoster virus (herpes zoster). Despite advances in the knowledge of …

Objectives Postherpetic neuralgia has various clinical features, and the implicated
pathophysiologic mechanisms are controversial. This study was carried out to clarify the …

Postherpetic neuralgia is an exceptionally drug-resistant neuropathic pain. To investigate
the pathophysiological mechanisms underlying postherpetic neuralgia we clinically …

Under normal conditions acute stimulation and sensitization of polymodal nociceptive C-
fibres cause pain and, due to afferent axon reflex activation, a local skin vasodilatation, flare …

Objective: The aim was to examine somatosensory profiles in the course of disease with
special regard to the different subtypes existing in PHN. Methods: Twenty patients with PHN …