Andrographolide ameliorates oxidative stress, inflammation and histological outcome in complete Freund's adjuvant-induced arthritis
S Luo, H Li, J Liu, X Xie, Z Wan, Y Wang, Z Zhao… - Chemico-biological …, 2020 - Elsevier
Objectives As one of the main active ingredients of Chinese herbal medicine Andrographis
paniculate, andrographolide is used in domestic clinical treatment for respiratory infections …
paniculate, andrographolide is used in domestic clinical treatment for respiratory infections …
Andrographolide attenuates complete freund's adjuvant induced arthritis via suppression of inflammatory mediators and pro-inflammatory cytokines
Ethnopharmacological relevance Traditional plant-derived medicines have enabled the
mankind in curing the wide spectrum of diseases throughout the ages. Andrographis …
mankind in curing the wide spectrum of diseases throughout the ages. Andrographis …
Andrographolide Benefits Rheumatoid Arthritis via Inhibiting MAPK Pathways
Z Li, J Tan, L Wang, Q Li - Inflammation, 2017 - Springer
Andrographolide (AD) is the main compound distributed in medicinal herb Andrographis
paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of …
paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of …
Inhibitory effects of andrographolide on activated macrophages and adjuvant-induced arthritis
Andrographolide, a diterpenoid lactone obtained from plant Andrographis paniculata, is
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …
Inhibition of matrix metalloproteinases and inducible nitric oxide synthase by andrographolide in human osteoarthritic chondrocytes
Q Ding, X Ji, Y Cheng, Y Yu, Y Qi… - Modern rheumatology, 2013 - academic.oup.com
Objective The aim of this study was to investigate the effects of andrographolide on matrix
metalloproteinases (MMP) 1, 3, and 13 and inducible nitric oxide synthase (iNOS) in human …
metalloproteinases (MMP) 1, 3, and 13 and inducible nitric oxide synthase (iNOS) in human …
Andrographolide ameliorates rheumatoid arthritis by regulating the apoptosis–NETosis balance of neutrophils
X Li, K Yuan, Q Zhu, Q Lu, H Jiang, M Zhu… - International journal of …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by symmetric
polyarthritis with swelling and pain at synovial joints. In RA patients, delayed neutrophil …
polyarthritis with swelling and pain at synovial joints. In RA patients, delayed neutrophil …
Anti-inflammatory effect of novel andrographolide derivatives through inhibition of NO and PGE2 production
GF Dai, J Zhao, ZW Jiang, LP Zhu, HW Xu… - International …, 2011 - Elsevier
Andrographolide (1) is a major diterpene lactone exhibiting anti-inflammatory effects and is
found in the plant Andrographis paniculata (Burm. f) Nees, which is widely used in …
found in the plant Andrographis paniculata (Burm. f) Nees, which is widely used in …
Inhibition of NF-κB expression and allergen-induced airway inflammation in a mouse allergic asthma model by andrographolide
Andrographolide from traditional Chinese herbal medicines previously showed it possesses
a strong anti-inflammatory activity. In present study, we investigated whether …
a strong anti-inflammatory activity. In present study, we investigated whether …
Andrographolide a new potential drug for the long term treatment of rheumatoid arthritis disease
MA Hidalgo, JL Hancke, JC Bertoglio… - Innovative …, 2013 - books.google.com
Andrographis paniculata,(Burm. f.) Wall. ex Nees, a herbaceous plant belonging to the
Family Acanthaceae, is one of the most commonly used medicinal plants in the traditional …
Family Acanthaceae, is one of the most commonly used medicinal plants in the traditional …
Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1–Nrf2–Are signaling pathway
B Li, T Jiang, H Liu, Z Miao, D Fang… - Journal of cellular …, 2019 - Wiley Online Library
Recent studies have shown that andrographolide (AP) has the potential to be developed as
a drug for therapy for osteoarthritis (OA). However, the role of AP in attenuating the …
a drug for therapy for osteoarthritis (OA). However, the role of AP in attenuating the …