On the basis of the biosynthesis of alkaloids derived from tryptophan and considering the
wide use of spirooxindole in drug molecular design, a series of novel spirooxindole …

On the basis of the scaffolds widely used in drug design, a series of novel spirooxindole
derivatives containing hydantoin, thiohydantoin, urea, and thiourea moieties have been …

The construction of libraries of stereoisomers of natural products serves as an important
approach to investigating the correlation between the stereostructure and biological activity …

Because gossypol and hemigossypol show antiviral activity but are structurally complex, we
designed and synthesized a series of structurally simpler phthalide and coumarin …

A series of novel penta-1, 4-diene-3-one oxime ether derivatives bearing a pyridine moiety
were designed and synthesized, and their antiviral activities against tobacco mosaic virus …

On the basis of our previous studies on the antiviral mechanism against tobacco mosaic
virus (TMV) and structure–activity relationship of phenanthroindolizidine alkaloids, a series …

Inspired by quinine and its analogues, we designed, synthesized, and evaluated two series
of quinoline small molecular compounds (a and 2a) and six series of quinoline derivatives …

We designed and synthesized a series of pyridine spiro derivatives and evaluated their
insecticidal and antiviral activities. Some compounds exhibited good insecticidal and …

Inspired by natural 2-quinolinecarboxylic acid derivatives, a series of quinoline compounds
containing acylhydrazine, acylhydrazone, sulfonylhydrazine, oxadiazole, thiadiazole, or …

Target compounds 4a− n were obtained by the reaction of 1-substituted phenyl-3-methyl-5-
substituted phenylthio-4-pyrazolaldoximes (3) with chloromethylated heterocyclic …