[HTML][HTML] Childhood obesity: a potential key factor in the development of glioblastoma multiforme

P Sachdeva, S Ghosh, S Ghosh, S Han, J Banerjee… - Life, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is a malignant primary tumor type of the central nervous
system (CNS). This type of brain tumor is rare and is responsible for 12–15% of all brain …

[HTML][HTML] Prognostic impact of obesity in newly-diagnosed glioblastoma: a secondary analysis of CeTeG/NOA-09 and GLARIUS

J Weller, N Schäfer, C Schaub, AL Potthoff… - Journal of neuro …, 2022 - Springer
Purpose The role of obesity in glioblastoma remains unclear, as previous analyses have
reported contradicting results. Here, we evaluate the prognostic impact of obesity in two trial …

An overview of mongenic and syndromic obesities in humans

WK Chung - Pediatric blood & cancer, 2012 - Wiley Online Library
Obesity is increasing in prevalence in the United States with over 65% of adults considered
overweight and 16% of children with BMI> 95 percentile. The heritability of obesity is …

The genetics of pediatric obesity

A Chesi, SFA Grant - Trends in Endocrinology & Metabolism, 2015 - cell.com
Obesity among children and adults has notably escalated over recent decades and
represents a global major health problem. We now know that both genetic and …

Overweight, obesity and adiposity in survivors of childhood brain tumours: a systematic review and meta‐analysis

KW Wang, A Fleming, DL Johnston, SM Zelcer… - Clinical …, 2018 - Wiley Online Library
Survivors of childhood brain tumours (SCBT) have increased cardiometabolic risks, but the
determinants of these risks are unclear. This systematic review aims to compare the …

Impact of body mass index on survival outcome in patients with newly diagnosed glioblastoma: a retrospective single-center study

JY Cha, JS Park, YK Hong… - Integrative Cancer …, 2021 - journals.sagepub.com
Introduction: The impact of obesity on survival outcomes in patients with glioblastoma (GBM)
has not been well reported and the results for patients are currently unclear. We investigated …

Association between body mass index and mortality in patients with glioblastoma mutliforme

LW Jones, F Ali-Osman, E Lipp, JE Marcello… - Cancer causes & …, 2010 - Springer
Purpose To examine the association between obesity and survival in patients with
glioblastoma mutliforme (GBM) Methods Using a prospective design, 1,259 patients with …

[HTML][HTML] Adiposity in childhood brain tumors: A report from the Canadian Study of Determinants of Endometabolic Health in Children (CanDECIDE Study)

KW Wang, RJ Souza, A Fleming, SK Singh… - Scientific reports, 2017 - nature.com
Children with brain tumors (CBT) are at high risk of cardiovascular diseases and type 2
diabetes compared to the general population. Recently, adiposity has been reported to be …

Body mass index as an independent prognostic factor in glioblastoma

P Valente Aguiar, B Carvalho, R Vaz… - Cancer Causes & Control, 2021 - Springer
Purpose Glioblastoma prognosis remains dismal despite gross total removal (GTR) followed
by chemoradiotherapy. Other known prognostic factors include functional status, age and …

[HTML][HTML] New insights regarding genetic aspects of childhood obesity: a minireview

CO Mǎrginean, C Mǎrginean, LE Meliţ - Frontiers in pediatrics, 2018 - frontiersin.org
Introduction: Childhood obesity is occurring at alarming rates in both developed and
developing countries.“Obesogenic” environmental factors must be associated with variants …