Phytopathogenic fungi remain a continuous and huge threat in the agricultural fields. The
agrochemical industry has made great development of the use of microbial natural products …

Tomato spotted wilt virus (TSWV) causes major losses of many crops worldwide. Several
strategies have been attempted to control disease caused by TSWV. However, many …

Natural products are one of the resources for discovering novel fungicidal leads. As a
natural fungicide, osthole was used as a coumarin-based lead compound for the …

Plant diseases caused by phytopathogenic fungi reduce the yield and quality of crops. To
develop novel antifungal agents, we designed and synthesized eight series of …

A series of C9-substituted phenanthrene-based tylophorine derivatives (PBTs) were
designed, synthesized, and first evaluated for their antiviral activities against tobacco mosaic …

Seventeen quinolizidine alkaloids, including two new ones, 5-hydoxy-7, 11-dehydromatrine
(1) and 11-hydroxylupanine (2), were isolated from the aerial parts of Sophora tonkinensis …

Ten eudesmanolides (1–10) including five new ones (1–4 and 6) were isolated from the
whole plant of Wedelia trilobata (L.) Hitchc., a notoriously invasive weed in South China. As …

3-Hydroxy-2-oxindole motif constitutes a core structure in numerous natural products and
imparts notable biological activities. Here, we describe the design and synthesis of four …

A total of 32 novel sulfoximines bearing cyanoguanidine and nitroguanidine moieties were
designed and synthesized by a rational molecule design strategy. The bioactivities of the …

Matrine, a quinolizidine alkaloid isolated from the roots of Sophora flavescens, is a naturally
non-food bioactive product. To discover new non-food bioactive product-based pesticides, a …