DNA methylation and the preservation of cell identity
O Bogdanović, R Lister - Current opinion in genetics & development, 2017 - Elsevier
DNA methylation is a major epigenetic modification of vertebrate genomes that is mostly
associated with transcriptional repression. During embryogenesis, DNA methylation …
associated with transcriptional repression. During embryogenesis, DNA methylation …
[PDF][PDF] Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development.
Genes constitute only a small proportion of the mammalian genome, the majority of which is
composed of non-genic repetitive elements including interspersed repeats and satellites. A …
composed of non-genic repetitive elements including interspersed repeats and satellites. A …
New insights into mechanisms that regulate DNA methylation patterning
G Ficz - Journal of Experimental Biology, 2015 - journals.biologists.com
From a fertilised egg to a mature organism, cells divide and accumulate epigenetic
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …
Emerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns
DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …
regulation and development. DNA methylation patterns are established during early …
DNA methylation dynamics in cellular commitment and differentiation
M Suelves, E Carrió, Y Núñez-Álvarez… - Briefings in functional …, 2016 - academic.oup.com
DNA methylation is an essential epigenetic modification for mammalian development and is
crucial for the establishment and maintenance of cellular identity. Traditionally, DNA …
crucial for the establishment and maintenance of cellular identity. Traditionally, DNA …
DNA methylation in animal development
RR Meehan - Seminars in cell & developmental biology, 2003 - Elsevier
Nuclear transfer experiments have demonstrated that epigenetic mechanisms operate to
limit gene expression during animal development. In somatic cells, silenced genes are …
limit gene expression during animal development. In somatic cells, silenced genes are …
DNA methylation in early development
TM Geiman, K Muegge - Molecular Reproduction and …, 2010 - Wiley Online Library
Abstract Development from separate parental germ cells through fertilization and
proceeding to a fully functioning adult animal occurs through an intricate program of …
proceeding to a fully functioning adult animal occurs through an intricate program of …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …
methylation has numerous functions: it is implicated in the repression of transposons and …
DNA methylation in mouse embryonic stem cells and development
Mammalian development is associated with considerable changes in global DNA
methylation levels at times of genomic reprogramming. Normal DNA methylation is essential …
methylation levels at times of genomic reprogramming. Normal DNA methylation is essential …
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
Methylation of DNA is an essential epigenetic control mechanism in mammals. During
embryonic development, cells are directed toward their future lineages, and DNA …
embryonic development, cells are directed toward their future lineages, and DNA …
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- histone modification dna methylation
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