Aberrant or elevated levels of reactive oxygen species (ROS) can mediate deleterious
cellular effects, including neuronal toxicity and degeneration observed in the etiology of a …

Reactive oxygen species (ROS) have emerged as regulators of key processes supporting
neuronal growth, function, and plasticity across lifespan. At normal physiological levels, ROS …

Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …

Cellular homeostasis plays a critical role in how an organism will develop and age.
Disruption of this fragile equilibrium is often associated with health degradation and …

Historically, ROS have been considered toxic molecules, especially when their intracellular
concentration reaches high values. However, physiological levels of ROS support crucial …

The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …

In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

Increasing evidence suggests that reactive oxygen species (ROS), such as superoxide and
hydrogen peroxide, act as necessary signaling molecules in processes underlying …

Significance: Numerous studies have demonstrated the actions of reactive oxygen species
(ROS) as regulators of several physiological processes. In this study, we discuss how redox …

Mounting evidence points to a role for endogenous reactive oxygen species (ROS) in cell
signaling, including in the control of cell proliferation, differentiation, and fate. However, the …