Poor cell survival limits the beneficial impact of mesenchymal stem cell transplantation on acute kidney injury
VR Burst, M Gillis, F Pütsch, R Herzog… - Nephron Experimental …, 2010 - karger.com
Background: Although renal tubular epithelium has a great capacity for repair it has been
suggested that the administration of mesenchymal stem cells may accelerate the recovery …
suggested that the administration of mesenchymal stem cells may accelerate the recovery …
Therapeutic applications of mesenchymal stem cells to repair kidney injury
H Asanuma, DR Meldrum, KK Meldrum - The Journal of urology, 2010 - Elsevier
PURPOSE: The potential use of stem cells for acute and chronic renal injury is under
intensive investigation. We summarized the current literature on the potential therapeutic …
intensive investigation. We summarized the current literature on the potential therapeutic …
The regenerative potential of stem cells in acute renal failure
Adult stem cells have been characterized in several tissues as a subpopulation of cells able
to maintain, generate, and replace terminally differentiated cells in response to physiological …
to maintain, generate, and replace terminally differentiated cells in response to physiological …
Mesenchymal stem cells in acute kidney injury
BD Humphreys, JV Bonventre - Annu. Rev. Med., 2008 - annualreviews.org
The potential role of mesenchymal stem cells (MSCs, also called mesenchymal stromal
cells) in endogenous repair and cell-based therapies for acute kidney injury (AKI) is under …
cells) in endogenous repair and cell-based therapies for acute kidney injury (AKI) is under …
Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
F Togel, Z Hu, K Weiss, J Isaac… - American Journal …, 2005 - journals.physiology.org
Severe acute renal failure (ARF) remains a common, largely treatment-resistant clinical
problem with disturbingly high mortality rates. Therefore, we tested whether administration of …
problem with disturbingly high mortality rates. Therefore, we tested whether administration of …
[HTML][HTML] Mesenchymal stem cells, not conditioned medium, contribute to kidney repair after ischemia-reperfusion injury
L Xing, R Cui, L Peng, J Ma, X Chen, RJ Xie… - Stem cell research & …, 2014 - Springer
Introduction Studies have shown that stem cells exert their therapeutic effects on acute
kidney injury (AKI) through paracrine/endocrine actions. If the protective effect is mediated in …
kidney injury (AKI) through paracrine/endocrine actions. If the protective effect is mediated in …
Contribution of stem cells to kidney repair
B Bussolati, PV Hauser, R Carvalhosa… - Current stem cell …, 2009 - ingentaconnect.com
A current explanation for development of chronic renal injury is the imbalance between
injurious mechanism and regenerative repair. The possibility that stem cells contribute to the …
injurious mechanism and regenerative repair. The possibility that stem cells contribute to the …
The role of mesenchymal stem cells in the functional improvement of chronic renal failure
S Choi, M Park, J Kim, S Hwang, S Park… - Stem cells and …, 2009 - liebertpub.com
The most commonly used therapeutic targets in nephrology are the reduction of injury, the
delay of progression, or renal replacement therapy. Many animal and human studies …
delay of progression, or renal replacement therapy. Many animal and human studies …
Stem cells in acute kidney injury
B Bussolati, G Camussi - Acute Kidney Injury, 2007 - karger.com
The susceptibility of developing acute renal failure depends on the ability of the kidney to
recover from acute injury and regain normal function. Recently, the possible contribution of …
recover from acute injury and regain normal function. Recently, the possible contribution of …
Not a process of simple vicariousness, the differentiation of human adipose-derived mesenchymal stem cells to renal tubular epithelial cells plays an important role in …
K Li, Q Han, X Yan, L Liao, RC Zhao - Stem cells and development, 2010 - liebertpub.com
The recent findings indicate that under conditions of severe tubular injuries, transplantation
of mesenchymal stem cells (MSCs) may be a promising treatment in acute kidney diseases; …
of mesenchymal stem cells (MSCs) may be a promising treatment in acute kidney diseases; …
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