In the mouse, the earliest heart precursors can be traced to approximately 50 founder cells
located on both sides of the midline in the epiblast of early gastrula stage embryos (E6 …

In this review we discuss the major morphogenetic and regulative events that control
myocardial progenitor cells from the time that they delaminate from the epiblast in the …

In gastrulation stage embryos of birds and mammals, the heart field is established as
mesodermal crescents flanking the area rostrolateral to Hensen's node. Subsequent fusion …

In amniote embryos, cells from a rostral portion of the primitive streak migrate anterolaterally
and establish the heart field mesoderm, from which two cardiac cell lineages …

Publisher Summary To understand the molecular mechanisms that govern sequentially
programmed development and integration of these subcardiac components during heart …

Studies of vertebrate heart development have identified key genes and signalling molecules
involved in the formation of a myocardial tube from paired heart-forming fields in splanchnic …

As classically described, the precardiac mesoderm of the paired heart-forming fields migrate
and fuse anteriomedially in the ventral midline to form the first segment of the straight heart …

The developing heart in avian embryos has been examined extensively over the past
several decades using classic embryologic and, more recently, molecular and genetic …

The heart develops from 2 sources of mesoderm progenitors, the first and second heart field
(FHF and SHF). Using a single-cell transcriptomic assay combined with genetic lineage …

In human development, it is postulated based on histological sections, that the cardiogenic
mesoderm rotates 180° with the pericardial cavity. This is also thought to be the case in …