Over the last decade, mitochondrial dynamics beyond function during axon regeneration/
degeneration have received attention. Axons have an effective delivery system of …

Mitochondria are organelles responsible for bioenergetic metabolism, calcium homeostasis,
and signal transmission essential for neurons due to their high energy consumption …

Axon regeneration is essential to restore the nervous system after axon injury. However, the
neuronal cell biology that underlies axon regeneration is incompletely understood. Here we …

In this issue of Neuron, Han et al.(2016) and Cartoni et al.(2016) define a critical role of
mitochondrial transport for successful axon regeneration after injury and provide new …

Mitochondria are dynamic organelles that undergo transport, fission, and fusion. The three
main functions of mitochondria are to generate ATP, buffer cytosolic calcium, and generate …

Axonal degeneration is a major contributor to neuronal dysfunction in many neurological
conditions and has additional roles in development. It can be triggered by divergent stimuli …

Mitochondrial transport is essential for neuronal function, but the evidence of connections
between mitochondrial transport and axon regeneration in the central nervous system (CNS) …

The importance of mitochondria for neuronal function is evident by the large number of
neurodegenerative diseases that have been associated with a disruption of mitochondrial …

Axonal homeostasis is maintained by processes that include cytoskeletal regulation, cargo
transport, synaptic activity, ionic balance, and energy supply. Several of these processes …

Appropriate distribution and supply of mitochondria to critical neuronal sites are thought to
be necessary for the normal maintenance of neuronal architecture and activity, including …