Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

Abstract Purpose of Review In the rapidly developing field of adoptive cell immunotherapy,
there is urgent need for discoveries that would improve outcomes, extend the applicability …

The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …

In recent years, great strides have been made toward the development of immune cell‐
based therapies in the treatment of refractory malignancies. Primary T cells and NK cells …

Human pluripotent stem cells (PSCs) provide a promising resource to produce immune cells
for adoptive cellular immunotherapy to better treat and potentially cure otherwise lethal …

Induced pluripotent stem cells (iPSCs) are mainly characterized by their unlimited
proliferation abilities and potential to develop into almost any cell type. The creation of this …

Despite recent advances in cancer treatment over the past 30 years, therapeutic options
remain limited and do not always offer a cure for malignancy. Given that tumor-associated …

Chimeric antigen receptor T (CAR-T) cell therapy has been increasingly conducted for
cancer patients in clinical settings. Progress in this therapeutic approach is hampered by the …

The development of methods to derive induced pluripotent stem cells (iPSCs) has propelled
stem cell research, and has the potential to revolutionize many areas of medicine, including …

Engineered T cells have been shown to be highly effective in cancer immunotherapy,
although T cell exhaustion presents a challenge for their long-term function. Additional T-cell …