Abstract Antigen-presenting cells (APCs), such as dendritic cells (DCs) and macrophages,
are important regulators of the immune system, as they connect the innate and adaptive …

Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells
biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer …

Avoiding the immune rejection of transplanted T cells is central to the success of allogeneic
cancer immunotherapies. One solution to protecting T-cell grafts from immune rejection …

Adoptive transfer of antitumor lymphocytes has gained intense interest in the field of cancer
therapeutics over the past two decades. Human natural killer (NK) cells are a promising …

Current approaches to adoptive T-cell therapy are limited by the difficulty of obtaining
sufficient numbers of T cells against targeted antigens with useful in vivo characteristics …

The use of induced pluripotent stem cells (iPSCs) is an exciting frontier in the study and
treatment of human diseases through the generation of specific cell types. Here we show the …

Autoimmune diseases (AIDs), a heterogeneous group of immune-mediated disorders, are a
major and growing health problem. Although AIDs are currently treated primarily with anti …

The use of allogeneic, pluripotent stem‐cell‐derived immune cells for cancer
immunotherapy has been the subject of recent clinical trials. In Japan, investigator‐initiated …

Abstract Purpose of Review The goal of this paper is to highlight the major challenges in the
translation of human pluripotent stem cells into a clinical setting. Recent Findings Innate …

Autologous‐induced pluripotent stem cells (iPSCs) may eventually be used in cell
replacement therapies to treat a wide range of diseases and have been touted as a solution …