Integrated generation of induced pluripotent stem cells in a low-cost device

H Lin, Q Li, Q Du, O Wang, Z Wang, L Akert… - Biomaterials, 2019 - Elsevier
Human induced pluripotent stem cells (iPSCs) have unlimited proliferation capability and
potential to differentiate into all somatic cells. Their derivatives contain patients' genetic …

[HTML][HTML] Overview: an iPS cell stock at CiRA

M Umekage, Y Sato, N Takasu - Inflammation and regeneration, 2019 - Springer
Induced pluripotent stem cells (iPSCs) can be produced from various somatic cells and have
the ability to differentiate into various cells and tissues of the body. Regenerative medicine …

Pluripotent stem cell–based cancer therapy: Promise and challenges

SJ Sharkis, RJ Jones, C Civin, YY Jang - Science translational …, 2012 - science.org
The development of induced pluripotent stem cell (iPSC) technology has generated
enthusiasm about the therapeutic potential of these cells for treating a variety of diseases …

[HTML][HTML] Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells

H Watarai, S Fujii, D Yamada… - The Journal of …, 2010 - Am Soc Clin Investig
NKT cells demonstrate antitumor activity when activated to produce Th1 cytokines by DCs
loaded with α-galactosylceramide, the prototypic NKT cell–activating glycolipid antigen …

Progress and promise towards safe induced pluripotent stem cells for therapy

A Seifinejad, M Tabebordbar, H Baharvand… - Stem Cell Reviews and …, 2010 - Springer
The recent generation of induced pluripotent stem cells (iPSCs) from somatic cells provides
an invaluable resource for drug or toxicology screening, medical research, and patient …

Human iPS cell–derived hematopoietic progenitor cells induce T-cell anergy in in vitro–generated alloreactive CD8+ T cells

EM Kim, G Manzar, N Zavazava - Blood, The Journal of the …, 2013 - ashpublications.org
Human induced pluripotent stem cells (iPSCs) have emerged as an alternative source of
pluripotent stem cells that can be used for tissue regeneration in place of the controversial …

[HTML][HTML] Improved safety of induced pluripotent stem cell-derived antigen-presenting cell-based cancer immunotherapy

H Mashima, R Zhang, T Kobayashi… - … Therapy-Methods & …, 2021 - cell.com
The tumorigenicity and toxicity of induced pluripotent stem cells (iPSCs) and their derivatives
are major safety concerns in their clinical application. Recently, we developed granulocyte …

[HTML][HTML] Induced pluripotent stem cells: applications in regenerative medicine, disease modeling, and drug discovery

VK Singh, M Kalsan, N Kumar, A Saini… - Frontiers in cell and …, 2015 - frontiersin.org
Recent progresses in the field of Induced Pluripotent Stem Cells (iPSCs) have opened up
many gateways for the research in therapeutics. iPSCs are the cells which are …

[HTML][HTML] Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors

R Guo, F Hu, Q Weng, C Lv, H Wu, L Liu, Z Li, Y Zeng… - Cell Research, 2020 - nature.com
Achievement of immunocompetent and therapeutic T lymphopoiesis from pluripotent stem
cells (PSCs) is a central aim in T cell regenerative medicine. To date, preferentially …

Current advances in the generation of human iPS cells: implications in cell‐based regenerative medicine

A Revilla, C González, A Iriondo… - Journal of tissue …, 2016 - Wiley Online Library
Over the last few years, the generation of induced pluripotent stem cells (iPSCs) from human
somatic cells has proved to be one of the most potentially useful discoveries in regenerative …