Development of stem cell-derived immune cells for off-the-shelf cancer immunotherapies

YR Li, ZS Dunn, Y Zhou, D Lee, L Yang - Cells, 2021 - mdpi.com
Cell-based cancer immunotherapy has revolutionized the treatment of hematological
malignancies. Specifically, autologous chimeric antigen receptor-engineered T (CAR-T) cell …

Applications of iPSCs in cancer research: supplementary issue: stem cell biology

JJ Kim - Biomarker insights, 2015 - journals.sagepub.com
Induced pluripotent stem cells (iPSCs) derived from reprogrammed somatic cells are
emerging as one of the most versatile tools in biomedical research and pharmacological …

Modulation of human allogeneic and syngeneic pluripotent stem cells and immunological implications for transplantation

SD Sackett, ME Brown, DM Tremmel, T Ellis… - Transplantation …, 2016 - Elsevier
Tissues derived from induced pluripotent stem cells (iPSCs) are a promising source of cells
for building various regenerative medicine therapies; from simply transplanting cells to …

Induced pluripotent stem cells (iPSCs)—roles in regenerative therapies, disease modelling and drug screening

MAM Aboul-Soud, AJ Alzahrani, A Mahmoud - Cells, 2021 - mdpi.com
The discovery of induced pluripotent stem cells (iPSCs) has made an invaluable contribution
to the field of regenerative medicine, paving way for identifying the true potential of human …

Translational prospects for human induced pluripotent stem cells

M Csete - Regenerative medicine, 2010 - Taylor & Francis
The pace of research on human induced pluripotent stem (iPS) cells is frantic worldwide,
based on the enormous therapeutic potential of patient-specific pluripotent cells free of the …

An overview of reprogramming approaches to derive integration-free induced pluripotent stem cells for prospective biomedical applications

C Dey, K Raina, KK Haridhasapavalan, M Thool… - Recent advances in …, 2021 - Elsevier
The remarkable discovery of the derivation of induced pluripotent stem cells (iPSCs)
heralded the development of a new technological platform for therapeutic applications in …

Towards personalized regenerative cell therapy: mesenchymal stem cells derived from human induced pluripotent stem cells

L Lin, L Bolund, Y Luo - Current stem cell research & therapy, 2016 - ingentaconnect.com
Mesenchymal stem cells (MSCs) are adult stem cells with the capacity of self-renewal and
multilineage differentiation, and can be isolated from several adult tissues. However …

Evolution of induced pluripotent stem cell technology

H Zhou, S Ding - Current opinion in hematology, 2010 - journals.lww.com
Summary iPSC technology provides unprecedented opportunities in biomedical research
and regenerative medicine. However, there remain a great deal to learn about iPSC safety …

Induced pluripotent stem cells: origins, applications, and future perspectives

J Zhao, W Jiang, C Sun, C Hou, X Yang… - Journal of Zhejiang …, 2013 - Springer
Embryonic stem (ES) cells are widely used for different purposes, including gene targeting,
cell therapy, tissue repair, organ regeneration, and so on. However, studies and applications …

Pluripotent stem cell-derived natural killer cells for cancer therapy

DA Knorr, DS Kaufman - Translational Research, 2010 - Elsevier
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) provide
an accessible, genetically tractable, and homogenous starting cell population to study …