Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines

R Barrett, L Ornelas, N Yeager… - Stem cells …, 2014 - academic.oup.com
Patient-specific induced pluripotent stem cells (iPSCs) hold great promise for many
applications, including disease modeling to elucidate mechanisms involved in disease …

[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

[HTML][HTML] Recent policies that support clinical application of induced pluripotent stem cell-based regenerative therapies

K Azuma, S Yamanaka - Regenerative Therapy, 2016 - Elsevier
In Japan, a research center network consisting of Kyoto University to provide clinical-grade
induced Pluripotent Stem Cells (iPSC) and several major research centers to develop iPSC …

[HTML][HTML] An overview of direct somatic reprogramming: the ins and outs of iPSCs

S Menon, S Shailendra, A Renda, M Longaker… - International journal of …, 2016 - mdpi.com
Stem cells are classified into embryonic stem cells and adult stem cells. An evolving
alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs) …

Induced pluripotent stem cells and their use in human models of disease and development

P Karagiannis, K Takahashi, M Saito… - Physiological …, 2019 - journals.physiology.org
The discovery of somatic cell nuclear transfer proved that somatic cells can carry the same
genetic code as the zygote, and that activating parts of this code are sufficient to reprogram …

[HTML][HTML] Haplobanking induced pluripotent stem cells for clinical use

S Sullivan, PJ Fairchild, SGE Marsh, CR Müller… - Stem Cell Research, 2020 - Elsevier
The development of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka and
colleagues in 2006 has led to a potential new paradigm in cellular therapeutics, including …

[HTML][HTML] Inducing iPSCs to escape the dish

B Barrilleaux, PS Knoepfler - Cell Stem Cell, 2011 - cell.com
Induced pluripotent stem cells (iPSCs) hold great promise for autologous cell therapies, but
significant roadblocks remain to translating iPSCs to the bedside. For example, concerns …

iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapy

F Cichocki, R Bjordahl, S Gaidarova… - Science translational …, 2020 - science.org
The development of immunotherapeutic monoclonal antibodies targeting checkpoint
inhibitory receptors, such as programmed cell death 1 (PD-1), or their ligands, such as PD …

Generation of mouse and human induced pluripotent stem cells (iPSC) from primary somatic cells

IM Lorenzo, A Fleischer, D Bachiller - Stem Cell Reviews and Reports, 2013 - Springer
Cellular reprogramming consists of the conversion of differentiated cells into pluripotent
cells; the so-called induced Pluripotent Stem Cells. iPSC are amenable to in vitro …

[HTML][HTML] Cancer cells as a new source of induced pluripotent stem cells

A Shamsian, R Sahebnasagh, A Norouzy… - Stem Cell Research & …, 2022 - Springer
Over the last 2 decades, induced pluripotent stem cells (iPSCs) have had various potential
applications in various medical research areas, from personalized medicine to disease …