T cells, as orchestrators of the adaptive immune response, serve important physiological
and potentially therapeutic roles, for example in cancer immunotherapy. T cells are readily …

Natural killer (NK) cells are a part of innate immunity that can be activated rapidly in
response to malignant transformed cells without prior sensitization. Engineering NK cells to …

Invariant natural killer T (iNKT) cells are a subset of innate-like T cells restricted by a major
histocompatibility complex (MHC) class I-like molecule, CD1d. iNKT cells express an …

Although adoptive transfer of cytotoxic T lymphocytes (CTL) offer a promising cancer
therapeutic direction, the generation of antigen-specific CTL from patients has faced difficulty …

Macrophages derived from human induced pluripotent stem cells (iPSCs) have the potential
to enable the development of cell-based therapies for numerous disease conditions. We …

Clinical successes demonstrated by chimeric antigen receptor T-cell immunotherapy have
facilitated further development of T-cell immunotherapy against wide variety of diseases …

Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago,
enormous progress has been made in stem cell biology and regenerative medicine. Human …

Recent outstanding clinical results produced by engineered T cells, including chimeric
antigen receptors, have already facilitated further research that broadens their applicability …

The development of induced pluripotent stem cells (iPS cells) has raised the prospect of
patient-specific treatments for various diseases. Theoretically, iPS cell technology avoids the …

Generation of induced pluripotent stem (iPS) cells has revolutionized the field of
regenerative medicine. With the exponential increase in iPS cell research in the past three …