Effect of gender and estrous cycle on the pharmacokinetics of ethanol in the rat brain

DL Robinson, LJ Brunner… - Alcoholism: Clinical and …, 2002 - Wiley Online Library
Background: Aspects of ethanol pharmacokinetics in the blood, such as elimination, are
known to vary by gender in the rat. Ethanol concentrations reaching the brain, which are …

Kinetics of ethanol metabolism in the intact rat and monkey

AB Makar, GJ Mannering - Biochemical Pharmacology, 1970 - Elsevier
Because ethanol distributes evenly throughout body water and because it can be given in
saturating doses, it offers an opportunity for a comparison of kinetic studies in vivo with those …

First pass metabolism of ethanol-A gastrointestinal barrier against the systematic toxicity of ethanol

RJK Julkunen, C Di Padova, CS Lieber - Life sciences, 1985 - Elsevier
Both in men and rats, most of the ethanol ingested at a low dose is metabolized before it
reaches the systemic circulation. Oxidation of ethanol (mainly in the stomach) accounts for …