Directions for research in the post-myocardial infarction patient with left ventricular dysfunction

ME Harinstein, JD Flaherty, GC Fonarow… - American Journal of …, 2008 - ajconline.org
Left ventricular dysfunction (LVD) in post-myocardial infarction (MI) patients is an important
predictor of a poor prognosis. LVD may be asymptomatic in the post-MI patient, but it can …

Mechanisms of postinfarct left ventricular remodeling

BA French, CM Kramer - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier
Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

Postinfarction left ventricular remodeling: a pathophysiological and therapeutic review

Z Yousef, SR Redwood, MS Marber - Cardiovascular drugs and therapy, 2000 - Springer
Over the last 50 years, studies investigating the pathogenesis of left ventricular dysfunction
have resulted in many potential therapeutic targets being identified and novel classes of …

Relation between left ventricular remodeling and clinical outcomes in heart failure patients with left ventricular systolic dysfunction

JE Udelson, MA Konstam - Journal of cardiac failure, 2002 - Elsevier
Background: A major advance in understanding the pathophysiology of the heart failure
syndrome has been an understanding of the process of left ventricular (LV) remodeling. After …

Left ventricular remodeling: pathophysiology and treatment.

N Sharpe - Heart Failure Monitor, 2003 - europepmc.org
Left ventricular (LV) remodeling, which can result from myocardial damage or ventricular
pressure or volume overload, has genomic, cellular, and interstitial components with …

Heart failure after myocardial infarction: clinical implications and treatment

MF Minicucci, PS Azevedo, BF Polegato… - Clinical …, 2011 - Wiley Online Library
Heart failure is a frequent complication of myocardial infarction. Several factors, such as
recurrent myocardial ischemia, infarct size, ventricular remodeling, stunned myocardium …

Prevention of heart failure and postinfarction remodeling

PC Deedwania - Cardiology Clinics, 1994 - cardiology.theclinics.com
Considerable efforts have been made during the past decade to understand better the
pathophysiologic processes involved in LV remodeling and the progression of LV …

New concepts in post-infarction ventricular remodeling.

JE Udelson, RD Patten, MA Konstam - Reviews in cardiovascular …, 2003 - europepmc.org
An understanding of the process of left ventricular (LV) remodeling has led to greater
knowledge of the pathophysiology of heart failure syndrome. This article examines the …

The time course of left ventricular remodeling after acute myocardial infarction

SP Glasser - American Journal of Cardiology, 1997 - ajconline.org
Myocardial infarction (MI) is a leading cause of heart failure. MI is associated with a 7-to 10-
fold greater risk of developing heart failure compared with a normal population. Left …

Prevention of late postmyocardial infarction left ventricular remodeling: an update

F Mookadam, SE Moustafa - Current heart failure reports, 2009 - Springer
Cardiac remodeling remains an important primary therapeutic target in patients with
myocardial infarction (MI) and chronic heart failure. It also has utility as a reliable surrogate …