Targeting thyroid cancer microenvironment: basic research and clinical applications

C Nucera - Frontiers in Endocrinology, 2013 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy and its incidence has increased
considerably over the past few decades (1). This Research Topic is devoted to …

Guard your master: Thyroid hormone receptors protect their gland of origin from thyroid cancer

J Köhrle - Endocrinology, 2004 - academic.oup.com
Thyroid cancers constitute the most frequent endocrine neoplasia with an incidence of one
to four new cases per 100,000 persons per year, remarkably with 2-to 3-fold higher …

[HTML][HTML] Gene expression profiling of normal thyroid tissue from patients with thyroid carcinoma

R Ria, V Simeon, A Melaccio, G Di Meo, S Trino… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Gene expression profiling (GEP) of normal thyroid tissue from 43 patients with thyroid
carcinoma, 6 with thyroid adenoma, 42 with multinodular goiter, and 6 with Graves-Basedow …

[图书][B] Molecular basis of thyroid cancer

NR Farid - 2005 - books.google.com
Thyroid cancer is the fastest growing cancer in the US, especially among women. Given the
relative success we have had in its treatment, there is a need to capitalize on it by better …

Sub-segmentation specific paradigms for better individualized management of poorly differentiated thyroid carcinoma: can a systematic approach be evolved?

S Basu, A Kalshetty - Nuclear Medicine Communications, 2020 - journals.lww.com
Poorly differentiated thyroid carcinoma (PDTC) comprises of a well-described entity within
the histopathological parlance of thyroid carcinoma, though its clinical behaviour and …

Orthotopic mouse models for the preclinical and translational study of targeted therapies against metastatic human thyroid carcinoma with BRAFV600E or wild-type …

ZA Antonello, C Nucera - Oncogene, 2014 - nature.com
Molecular signature of advanced and metastatic thyroid carcinoma involves deregulation of
multiple fundamental pathways activated in the tumor microenvironment. They include BRAF …

Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy

J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …

[HTML][HTML] The art and science of thyroid surgery in the age of genomics: 100 years after Theodor Kocher

S Gulec - Molecular Imaging and Radionuclide Therapy, 2017 - ncbi.nlm.nih.gov
Cancer is a disorder of the genome. The thyroid cancer genome is being decoded. Recent
studies have identified a mutation or a genetic alteration in 95% of thyroid cancers. The …

Updated review of nuclear molecular imaging of thyroid cancers

H Fu, R Sa, L Cheng, Y Jin, X Qiu, M Liu, L Chen - Endocrine Practice, 2021 - Elsevier
Objectives We initiate this comprehensive review to update the advances in this field by
objectively elucidating the efficacies of promising radiopharmaceuticals. Methods We …

The Next Generation of Orthotopic Thyroid Cancer Models: Immunocompetent Orthotopic Mouse Models of BRAFV600E-Positive Papillary and Anaplastic Thyroid …

P Vanden Borre, DG McFadden, V Gunda, PM Sadow… - Thyroid, 2014 - liebertpub.com
Background: While the development of new treatments for aggressive thyroid cancer has
advanced in the last 10 years, progress has trailed headways made with other …