Organotypic cultures of human skin were made using dermal fibroblasts seeded into a type I
collagen gel overlaid with epidermal keratinocytes. Full-thickness excision of tattoos was …

A living-skin equivalent useful as a skin replacement and as a model system for basic
studies has been fabricated and tested extensively, it consists of two components:(1) a …

The cultured skin substitute was created through successive cultivation of fibroblasts and
keratinocytes that were combined within a collagen matrix. This collagen matrix was …

Skin is the first tissue-engineered organ to have been successfully developed in the
laboratory, and it has been clinically available for use as epidermal sheets for some time. As …

The foundation of modern plastic surgery rests on the ancient discoveries by Hindu
surgeons that skin could be incised, mobilized, reshaped, and reimplanted.'These surgical …

The transplantation of a sufficient quantity of good quality skin is of great clinical importance.
Severe burn patients lack adequate skin donor sites to cover their wounds with autografts …

Composite-tissue (eg, hand allograft) allotransplantation is currently limited by the need for
immunosuppression to prevent graft rejection. Inducing a state of tolerance in the recipient …

Using inbred mouse strains C3H/He and BALB/c and an anti-class I MHC monoclonal
antibody, we examined the graftability of mixed cultures composed of syngeneic and …

Severe burn patients lack adequate skin donor sites to resurface their burn wounds. Patients
with severe burn injuries to areas such as an entire face are presently reconstructed with …

The article presents information on Keratinocyte Grafts and Skin Equivalents. Advances in
tissue culture methods permit the growth of these individual cells from small skin biopsy …