Altered expression of CXCR3 and CCR6 and their ligands in HTLV‐1 carriers and HAM/TSP patients

H Rafatpanah, M Felegari… - Journal of Medical …, 2017 - Wiley Online Library
Recruitment of leukocytes by chemokines and chemokine receptors to CNS plays a crucial
role in the induction of inflammatory response in HTLV‐1‐associated myelopathy/tropical …

Different roles of CXCR1 and CXCR2 in HTLV-1 carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients

T Rajaei, H Farajifard, SA Rezaee… - Medical Microbiology …, 2019 - Springer
One of the prominent features of HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is the excessive recruitment of leukocytes to the central nervous system (CNS) …

Local and systemic production of proinflammatory chemokines in the pathogenesis of HAM/TSP

M Guerra, T Luna, A Souza, C Amorim, NB Carvalho… - Cellular …, 2018 - Elsevier
Background HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) is
related with high proviral load, high proinflammatory cytokine levels, and passage of …

Levels of serum chemokines discriminate clinical myelopathy associated with human T lymphotropic virus type 1 (HTLV-1)/tropical spastic paraparesis (HAM/TSP) …

JB Guerreiro, SB Santos, DJ Morgan… - Clinical & …, 2006 - academic.oup.com
Approximately 5% of people infected with human T lymphotropic virus type 1 (HTLV-1)
develop clinical myelopathy or tropical spastic paraparesis (HAM/TSP) that is associated …

Plasmatic proinflammatory chemokines levels are tricky markers to monitoring HTLV‐1 carriers

DG Chaves, CC Sales… - Journal of Medical …, 2016 - Wiley Online Library
The human T‐cell leukemia virus type 1 (HTLV‐1) is present throughout the world and is
associated with HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of …

M Saito, H Sejima, T Naito, H Ushirogawa, T Matsuzaki… - Virology journal, 2017 - Springer
Background Chemokine (CC motif) ligand 1 (CCL1) is produced by activated monocytes/
macrophages and T-lymphocytes, and acts as a potent attractant for Th2 cells and a subset …

Mediators go together: high production of CXCL9, CXCL10, IFN-γ, and TNF-α in HTLV-1-associated myelopathy/tropical spastic paraparesis

HVPC Neco, VGS Teixeira… - AIDS research and …, 2017 - liebertpub.com
Abstract HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic
demyelinating and disabling syndrome caused by human T lymphotropic virus 1 (HTLV-1) …

Mediators Go Together: High Production of CXCL9, CXCL10, IFN-γ, and TNF-α in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis.

N HVPdC, V Teixeira, ACL Da Trindade… - AIDS research and …, 2017 - europepmc.org
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic
demyelinating and disabling syndrome caused by human T lymphotropic virus 1 (HTLV-1) …

CSF-chemokines in HTLV-I-associated myelopathy: CXCL10 up-regulation and therapeutic effect of interferon-α

K Narikawa, K Fujihara, T Misu, J Feng… - Journal of …, 2005 - Elsevier
We measured four chemokines in the cerebrospinal fluid (CSF) in human T-lymphotropic
virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) with …

Cerebrospinal fluid CXCL10 as a candidate surrogate marker for HTLV-1-associated myelopathy/tropical spastic paraparesis

K Tamaki, T Sato, J Tsugawa, S Fujioka… - Frontiers in …, 2019 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a debilitating, progressive disease without effective treatment; …