Evaluation of HTLV‐1 HBZ and proviral load, together with host IFN λ3, in pathogenesis of HAM/TSP

SH Mozhgani, N Jaberi, SA Rezaee… - Journal of Medical …, 2017 - Wiley Online Library
Human T‐cell lymphotropic virus 1 (HTLV‐1) is associated with two progressive diseases:
HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T‐cell …

Interferon lambda family along with HTLV-1 proviral load, tax, and HBZ implicated in the pathogenesis of myelopathy/tropical spastic paraparesis

SH Mozhgani, HR Jahantigh, H Rafatpanah… - Neurodegenerative …, 2018 - karger.com
Abstract HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic
neuroinflammatory disease related to human T lymphotropic virus type 1 (HTLV-1) infection …

[HTML][HTML] Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP

T Naito, J Yasunaga, Y Mitobe, K Shirai, H Sejima… - Retrovirology, 2018 - Springer
Background Among human T cell leukemia virus type 1 (HTLV-1)-infected individuals, there
is an association between HTLV-1 tax subgroups (subgroup-A or subgroup-B) and the risk …

[HTML][HTML] Dynamic changes of post-translationally modified forms of CXCL10 and soluble DPP4 in HCV subjects receiving interferon-free therapy

EG Meissner, J Decalf, A Casrouge, H Masur, S Kottilil… - PloS one, 2015 - journals.plos.org
Serum levels of the interferon (IFN)-stimulated chemokine CXCL10 are increased during
chronic HCV infection and associate with outcome of IFN-based therapy. Elevated levels of …

[HTML][HTML] Clinical pathophysiology of human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis

Y Yamano, T Sato - Frontiers in microbiology, 2012 - frontiersin.org
Human T-lymphotropic virus type 1 (HTLV-1), a human retrovirus, is the causative agent of a
progressive neurological disease termed HTLV-1-associated myelopathy/tropical spastic …

[HTML][HTML] Coevolution of HTLV-1-HBZ, Tax, and proviral load with host IRF-1 and CCNA-2 in HAM/TSP patients

M Saffari, M Rahimzada, A Mirhosseini… - Infection, Genetics and …, 2022 - Elsevier
Abstract Background HTLV-1-associated myelopathy (HAM/TSP) is a progressive
neurodegenerative inflammatory condition of HTLV-1 infection. Viral-host interactions are a …

HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis Is Not Associated with SNP rs12979860 of the IL‐28B Gene

ACR Vallinoto, BB Santana, KSG Sá… - Mediators of …, 2015 - Wiley Online Library
The present study investigated the association between the rs12979860 polymorphism in
the IL‐28B gene and HTLV‐1 infection as well as the development of HTLV‐1‐associated …

Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in healthy virus carriers …

H Nose, M Saito, K Usuku, AH Sabouri… - Journal of …, 2006 - Springer
The authors have previously developed a logistic regression equation to predict the odds
that a human T-cell lymphotropic virus type 1 (HTLV-1)-infected individual of specified …

[HTML][HTML] Abnormally High Levels of Virus-Infected IFN-γ+CCR4+CD4+CD25+ T Cells in a Retrovirus-Associated Neuroinflammatory Disorder

Y Yamano, N Araya, T Sato, A Utsunomiya, K Azakami… - PloS one, 2009 - journals.plos.org
Background Human T-lymphotropic virus type 1 (HTLV-1) is a human retrovirus associated
with both HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), which is a …

[HTML][HTML] HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T …

ES Gudo, SD Silva-Barbosa, L Linhares-Lacerda… - Virology Journal, 2015 - Springer
Background The mechanisms through which HTLV-1 leads to and maintains damage in the
central nervous system of patients undergoing HTLV-1 associated myelopathy/tropical …