1H-1, 2, 3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation

K Kumar, B Pradines, M Madamet, R Amalvict… - European journal of …, 2014 - Elsevier
Abstract 1H-1, 2, 3-triazole tethered isatin-ferrocene conjugates were synthesized and
evaluated for their antiplasmodial activities against chloroquine-susceptible (3D7) and …

1H-1, 2, 3-Triazole-tethered isatin-7-chloroquinoline and 3-hydroxy-indole-7-chloroquinoline conjugates: Synthesis and antimalarial evaluation

R Raj, J Gut, PJ Rosenthal, V Kumar - Bioorganic & Medicinal Chemistry …, 2014 - Elsevier
Abstract A series of 1H-1, 2, 3-triazole-tethered isatin-7-chloroquinoline and 3-hydroxy-
indole-7-chloroquinoline conjugates have been synthesized and evaluated for their …

1H-1, 2, 3-triazole tethered mono-and bis-ferrocenylchalcone-β-lactam conjugates: synthesis and antimalarial evaluation

K Kumar, B Pradines, M Madamet, R Amalvict… - European Journal of …, 2014 - Elsevier
A series of ferrocenylchalcone-β-lactam conjugates were synthesized and evaluated against
3D7 (CQ-Sensitive) and W2 (CQ-Resistant) strains of Plasmodium falciparum. The SAR …

Ferrocene-pyrimidine conjugates: Synthesis, electrochemistry, physicochemical properties and antiplasmodial activities

R Chopra, C de Kock, P Smith, K Chibale… - European Journal of …, 2015 - Elsevier
The promise of hybrid antimalarial agents and the precedence set by the antimalarial drug
ferroquine prompted us to design ferrocene-pyrimidine conjugates. Herein, we report the …

4-Aminoquinoline-ferrocenyl-chalcone conjugates: Synthesis and anti-plasmodial evaluation

A Singh, J Gut, PJ Rosenthal, V Kumar - European Journal of Medicinal …, 2017 - Elsevier
A series of aliphatic and aromatic substituted 1H-1, 2, 3-triazole-tethered 4-amino-quinoline-
ferrocenylchalcone conjugates has been synthesized and evaluated for anti-plasmodial …

Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1, 2, 3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates

B Sharma, S Kaur, J Legac, PJ Rosenthal… - Bioorganic & Medicinal …, 2020 - Elsevier
Abstract A series of 1H-1, 2, 3-triazole/acylhydrazide-tethered tetrahydro-β-carboline-4-
aminoquinoline conjugates was synthesized with an aim to study their anti-plasmodial …

Evaluation of triazole and isoxazole derivatives as potential anti-infective agents

AH Tarawneh, LA Al-Momani, F León, SK Jain… - Medicinal Chemistry …, 2018 - Springer
A series of isoxazole and triazole derivatives, with interesting bioactive scaffolds, were
examined for their in vitro antibacterial, antifungal, and antiprotozoal activities. These …

Synthesis, antimalarial activity and cytotoxicity of 4-aminoquinoline–triazine conjugates

S Manohar, SI Khan, DS Rawat - Bioorganic & medicinal chemistry letters, 2010 - Elsevier
A series of 4-aminoquinoline–triazine conjugates with different substitution pattern have
been synthesized and evaluated for their in vitro antimalarial activity against chloroquine …

Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1, 2-disubstituted ferrocene hybrids

C De Lange, D Coertzen, FJ Smit, JF Wentzel… - Bioorganic & Medicinal …, 2018 - Elsevier
Artemisinin-ferrocene conjugates incorporating a 1, 2-disubstituted ferrocene analogous to
that embedded in ferroquine but attached via a piperazine linker to C10 of the artemisinin …

Pyrimidine-chloroquinoline hybrids: Synthesis and antiplasmodial activity

R Chopra, K Chibale, K Singh - European Journal of Medicinal Chemistry, 2018 - Elsevier
Abstract Triazole tethered 7-chloroquinoline-pyrimidine-5-carboxylate hybrids were
synthesized and evaluated for antiplasmodial activity against chloroquine sensitive (CQ S) …