Metabolic products of skeletal muscle contraction activate metaboreceptor muscle afferents
that reflexively increase sympathetic nerve activity (SNA) targeted to both resting and …

1 Sympathetically evoked vasoconstriction is modulated by skeletal muscle contraction, but
the underlying events are incompletely understood. During contraction, intramuscular …

We studied the effects of physiological rates (0-4 Hz) of sympathetic stimulation on blood
flow and oxygen consumption of extensor digitorum longus muscles isolated from …

The present work provides insight into the relative contribution of different mechanisms in
regulating sympathetic discharge to skin and skeletal muscle in humans. Activation of …

Exercise is a potent stimulus to activate the sympathetic nervous system. Previous work
suggests that metabolite-sensitive muscle afferents are activated near the point of fatigue …

We used microelectrode recordings of muscle sympathetic nerve activity (MSNA) from the
peroneal nerve in the leg during arm exercise in conscious humans to test the concept that …

The present review examines the control of muscle vascular conductance by the
sympathetic nervous system during exercise. 2. Evidence for tonic sympathetic neural …

Activation of a metabolically generated reflex in exercising skeletal muscle (muscle
metaboreflex) in humans is known to trigger increases in sympathetic nerve activity (SNA) to …

Reflex mechanisms from contracting skeletal muscle have been shown to be important for
cardiovascular, neuroendocrine, and extramuscular fuel-mobilization responses in exercise …

Gracilis muscles of anesthetized dogs were isolated and perfused with blood at constant
flow. Oxygen uptake (Vo2) was measured by spectrophotometry of paired arterial and …