OBJECTIVES: The development of commensal flora in infants has been shown to be
sensitive to antibiotic use. Altered intestinal flora is thought to contribute to the etiology of …

Background The composition of the intestinal microflora has been proposed as an important
factor in the development of inflammatory bowel diseases (IBD). Antibiotics have the …

Background Use of antibiotics in early life has been linked with childhood inflammatory
bowel disease (IBD), but data for adults are mixed, and based on smaller investigations that …

OBJECTIVE: To determine whether childhood antianaerobic antibiotic exposure is
associated with the development of inflammatory bowel disease (IBD). METHODS: This …

To determine whether childhood exposure to antibiotics is associated with the risk of
developing inflammatory bowel disease (IBD), the authors conducted a national, register …

Objective Earlier studies on antibiotics exposure and development of IBD (Crohn's disease
(CD) and ulcerative colitis (UC)) may have been biased by familial factors and …

Background The changing epidemiology of inflammatory bowel disease (IBD) in both the
developed and developing worlds may provide insights into disease aetiology. Factors that …

OBJECTIVES: The objective of this study was to perform a meta-analysis investigating
antibiotic exposure as a risk factor for developing inflammatory bowel disease (IBD) …

Adults with inflammatory bowel disease from North Carolina were questioned during 1986
and 1987 to assess risk due to a variety of childhood infections and treatments with …

Objective. An inappropriate immune response to normal bowel flora is implicated in the
etiology of Crohn's disease. Tolerance to bowel flora develops in infancy, so factors …