[HTML][HTML] Celecoxib induces apoptosis via a mitochondria‑dependent pathway in the H22 mouse hepatoma cell line
D Shao, M Kan, P Qiao, Y Pan… - Molecular …, 2014 - spandidos-publications.com
Celecoxib is a potent nonsteroidal anti-inflammatory drug that has demonstrated promise in
cancer chemoprevention and treatment. The present study was conducted to gain insight …
cancer chemoprevention and treatment. The present study was conducted to gain insight …
[HTML][HTML] Metronomic celecoxib therapy in clinically available dosage ablates hepatocellular carcinoma via suppressing cell invasion, growth, and stemness in pre …
Objective To investigate the anti-carcinogenic effect of metronomic Celecoxib (ie, frequent
administration in clinically available doses) against hepatocellular carcinoma (HCC) in the …
administration in clinically available doses) against hepatocellular carcinoma (HCC) in the …
Bazedoxifene exhibits growth suppressive activity by targeting interleukin‐6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in …
H Ma, D Yan, Y Wang, W Shi, T Liu, C Zhao… - Cancer …, 2019 - Wiley Online Library
The interleukin (IL)‐6/glycoprotein (GP) 130/signal transducer and activator of transcription
(STAT) 3 pathway is emerging as a target for the treatment of hepatocellular carcinoma. IL‐6 …
(STAT) 3 pathway is emerging as a target for the treatment of hepatocellular carcinoma. IL‐6 …
[HTML][HTML] Celecoxib induces cell death on non-small cell lung cancer cells through endoplasmic reticulum stress
B Kim, J Kim, YS Kim - Anatomy & Cell Biology, 2017 - synapse.koreamed.org
Cyclooxygenase-2 (COX-2) is an enzyme induced by various proinflammatory and
mitogenic stimuli. Celecoxib is a selective inhibitor of COX-2 that have been shown to affect …
mitogenic stimuli. Celecoxib is a selective inhibitor of COX-2 that have been shown to affect …
[HTML][HTML] ψ-Bufarenogin, a novel anti-tumor compound, suppresses liver cancer growth by inhibiting receptor tyrosine kinase-mediated signaling
J Ding, W Wen, D Xiang, P Yin, Y Liu, C Liu, G He… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Resistance of hepatocellular carcinoma (HCC) to existing chemotherapeutic agents largely
contributes to the poor prognosis of patients, and discovery of novel anti-HCC drug is in an …
contributes to the poor prognosis of patients, and discovery of novel anti-HCC drug is in an …
[HTML][HTML] Effect of celecoxib combined with chemotherapy drug on malignant biological behaviors of gastric cancer
C Meng, Z Lu, M Fang, X Zhou, K Dai… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Abstract Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, has been reported to
have antitumor effects. In some tumor models, the combination of celecoxib with …
have antitumor effects. In some tumor models, the combination of celecoxib with …
[HTML][HTML] The molecular mechanisms of celecoxib in tumor development
B Wen, YT Wei, LL Mu, GR Wen, K Zhao - Medicine, 2020 - journals.lww.com
Background: Clinical studies have shown that celecoxib can significantly inhibit the
development of tumors, and basic experiments and in vitro experiments also provide a …
development of tumors, and basic experiments and in vitro experiments also provide a …
The protective role of etoricoxib against diethylnitrosamine/2-acetylaminofluorene-induced hepatocarcinogenesis in wistar rats: The impact of NF-κB/COX-2/PGE2 …
G Ali, H Omar, F Hersi, A Abo-Youssef… - Current Molecular …, 2022 - ingentaconnect.com
Background: Liver cancer ranks as the 7th and 5th leading cause of cancer morbidity
worldwide in men and women, respectively. Hepatocellular Carcinoma (HCC) is the most …
worldwide in men and women, respectively. Hepatocellular Carcinoma (HCC) is the most …
[HTML][HTML] Novel combination of celecoxib and metformin improves the antitumor effect by inhibiting the growth of Hepatocellular Carcinoma
JW Hu, B Chen, J Zhang, YP Qi, JH Liang… - Journal of …, 2020 - ncbi.nlm.nih.gov
Objective: To explore the effect of COX-2 inhibitor celecoxib in combination with metformin
on the prevention of Hepatocellular carcinoma (HCC) and the mechanisms involved …
on the prevention of Hepatocellular carcinoma (HCC) and the mechanisms involved …
[HTML][HTML] Meloxicam executes its antitumor effects against hepatocellular carcinoma in COX-2-dependent and-independent pathways
X Dong, R Li, P Xiu, X Dong, Z Xu, B Zhai, F Liu… - PloS one, 2014 - journals.plos.org
Background Cyclooxygenase (COX)-2 is overexpressed in many types of cancers including
hepatocellular carcinoma (HCC). Meloxicam, a selective COX-2 inhibitor, has shown …
hepatocellular carcinoma (HCC). Meloxicam, a selective COX-2 inhibitor, has shown …