Bone sarcomas linked to radiotherapy and chemotherapy in children

MA Tucker, GJ D'Angio, JD Boice Jr… - … England Journal of …, 1987 - Mass Medical Soc
We estimated the risk of subsequent bone cancer among 9170 patients who had survived
two or more years after the diagnosis of a cancer in childhood. As compared with the …

Radiation dose, chemotherapy and risk of osteosarcoma after solid tumours during childhood

B Le Vu, F de Vathaire, A Shamsaldin… - … journal of cancer, 1998 - Wiley Online Library
Osteosarcoma is the most frequent second primary cancer occurring during the first 20 years
following treatment for a solid cancer in childhood. Using a cohort study of children treated …

Radiotherapy, alkylating agents, and risk of bone cancer after childhood cancer

MM Hawkins, LMK Wilson, HS Burton… - JNCI: Journal of the …, 1996 - academic.oup.com
Background Individuals who had cancer in childhood are at higher risk of developing bone
cancer than any other type of second primary cancer. Purpose Using the population-based …

The etiology of osteosarcoma

G Ottaviani, N Jaffe - Pediatric and adolescent osteosarcoma, 2010 - Springer
Studies to determine the etiology of osteosarcoma involve epidemiologic and environmental
factors and genetic impairments. Factors related to patient characteristics include age …

Bone sarcomas as second malignant neoplasms following childhood cancer

WA Newton Jr, AT Meadows, H Shimada, GR Bunin… - Cancer, 1991 - Wiley Online Library
This study explores the relationship between histologic variants of bone sarcomas and
previous therapy in patients in whom an unrelated malignant neoplasm had been …

Epidemiology of bone cancer in children

AG Glass, JF Fraumeni Jr - Journal of the National Cancer …, 1970 - academic.oup.com
In a search for etiologic clues to primary bone cancer in childhood, we examined 1,532
death certificates of all children in the United States dying from these neoplasms, 1960–66 …

Radiation dose, chemotherapy and risk of soft tissue sarcoma after solid tumours during childhood

A Menu‐Branthomme, C Rubino… - … journal of cancer, 2004 - Wiley Online Library
Soft tissue sarcoma (STS) is one of the most frequent second primary cancer that occurs
during the first 20 years following treatment for a solid cancer in childhood. Our aim was to …

Second neoplasms following megavoltage radiation in a pediatric population

RE Haselow, M Nesbit, LP Dehner, FM Khan… - Cancer, 1978 - Wiley Online Library
Previous reports of radiation‐related neoplasia have relied primarily upon patients treated
by orthovoltage to low doses for benign disease. This survey is believed to be the first to …

Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases

MD Tabone, P Terrier, H Pacquement… - Journal of clinical …, 1999 - ascopubs.org
PURPOSE: We analyzed the clinical features and outcome of patients with radiation-
associated osteosarcoma treated during the era of contemporary chemotherapy. PATIENTS …

Radiation-induced soft-tissue and bone sarcoma

JH Kim, FC Chu, HQ Woodard, MR Melamed, A Huvos… - Radiology, 1978 - pubs.rsna.org
From the records of Memorial Hospital of the past 50 years, 47 cases with an established
diagnosis of radiation-induced sarcoma were identified and divided into two groups: the first …