Background: Prostate cancer (PCa) harbors a myriad of genomic and epigenetic defects.
Cytosine methylation of CpG-rich promoter DNA is an important mechanism of epigenetic …

Prostate cancer (PCa) is the most prevalent cancer, a significant contributor to morbidity and
a leading cause of cancer-related death in men in Western industrialized countries. In …

The prostate gland is the most common site of cancer and the second leading cause of
cancer death in American men. Recent emerging molecular biological technologies help us …

There is increasing evidence that DNA methylation is a critical source of gene regulation. In
addition, interindividual differences in DNA methylation status in cancer related genes are …

Candidate gene-based studies have identified a handful of aberrant CpG DNA methylation
events in prostate cancer. However, DNA methylation profiles have not been compared on a …

Prostate cancer is the most common malignancy and the second leading cause of cancer
death among men in the United States. There are three well-established risk factors for …

Background Aberrant DNA methylation may promote prostate carcinogenesis. We
investigated epigenome‐wide DNA methylation profiles in prostate cancer (PCa) compared …

Many differentially methylated genes have been identified in prostate cancer (PCa),
primarily using candidate gene-based assays. Recently, several global DNA methylation …

DNA methylation is one of the most important epigenetic mechanisms in regulating gene
expression. Genome hypermethylation has been proposed as a critical mechanism in …

Increasing evidence suggests that aberrant DNA methylation changes may contribute to
prostate cancer (PCa) ethnic disparity. To comprehensively identify DNA methylation …