Genome editing represents a group of newly developed capabilities that allow nucleotide-
level targeting of genomic regions in a wide range of species. This chapter provides an …

Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …

The Promises and Challenges of Precision Gene Editing in Animals of Agricultural Importance
Page 1 3 We live in changing times—it has always been that way. But, now the times are …

As a new genetic engineering technology, gene editing can precisely modify the specific
gene sequence of the organism's genome. In the last 10 years, with the rapid development …

Livestock is an essential life commodity in modern agriculture involving breeding and
maintenance. The farming practices have evolved mainly over the last century for …

Genome editing in large animals has tremendous practical applications, from more accurate
models for medical research through improved animal welfare and production efficiency …

Since centuries, the traits for production and disease resistance are being targeted while
improving the genetic merit of domestic animals, using conventional breeding programs …

Sheep and goats are valuable livestock species that have been raised for their production of
meat, milk, fiber, and other by-products. Due to their suitable size, short gestation period …

Contents Genome modification at specific loci in livestock species was only achievable by
performing homologous recombination in somatic cells followed by somatic cell nuclear …

Many genetically engineered rat strains have been produced for biomedical research. The
simple and quick production of knock-out and knock-in rats is currently possible using …