Genome editing and genetic engineering in livestock for advancing agricultural and biomedical applications

BP Telugu, KE Park, CH Park - Mammalian Genome, 2017 - Springer
Genetic modification of livestock has a longstanding and successful history, starting with
domestication several thousand years ago. Modern animal breeding strategies …

Precision editing of large animal genomes

DF Carlson, MW Walton, SC Fahrenkrug, PB Hackett - Advances in …, 2012 - Elsevier
Transgenic animals are an important source of protein and nutrition for most humans and
will play key roles in satisfying the increasing demand for food in an ever-increasing world …

[PDF][PDF] Improving pig genetic resistance and muscle production through molecular biology

Q Kang, Y Hu, Y Zou, W Hu, L Li, F Chang, Y Li… - Proceedings, 10th World …, 2014 - asas.org
Genome modification technology of livestock has developed rapidly in recent years. We can
not only insert foreign genes or DNA into a specific locus or disrupt an endogenous locus by …

[HTML][HTML] Genome editing of pigs for agriculture and biomedicine

H Yang, Z Wu - Frontiers in Genetics, 2018 - frontiersin.org
Pigs serve as an important agricultural resource and animal model in biomedical studies.
Efficient and precise modification of pig genome by using recently developed gene editing …

[HTML][HTML] Genome edited sheep and cattle

C Proudfoot, DF Carlson, R Huddart, CR Long… - Transgenic …, 2015 - Springer
Genome editing tools enable efficient and accurate genome manipulation. An enhanced
ability to modify the genomes of livestock species could be utilized to improve disease …

Innovative Approaches to Genome Editing in Chickens

OY Barkova, TA Larkina, AA Krutikova, EA Polteva… - Cytology and …, 2022 - Springer
Obtaining productive animals, including chickens, with specified characteristics is a
promising area of modern animal husbandry. The most relevant traits for chickens are …

[HTML][HTML] Zygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs

KM Whitworth, JA Benne, LD Spate, SL Murphy… - Transgenic …, 2017 - Springer
The CRISPR/Cas9 genome editing tool has increased the efficiency of creating genetically
modified pigs for use as biomedical or agricultural models. The objectives were to determine …

Gene targeting in rabbits: single-step generation of knock-out rabbits by microinjection of CRISPR/Cas9 plasmids

Y Kawano, A Honda - Genome Editing in Animals: Methods and Protocols, 2017 - Springer
The development of genome editing technology has allowed gene disruptions to be
achieved in various animal species and has been beneficial to many mammals. Gene …

Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

S Remy, L Tesson, S Menoret, C Usal… - Genome …, 2014 - genome.cshlp.org
The generation of genetically modified animals is important for both research and
commercial purposes. The rat is an important model organism that until recently lacked …

[HTML][HTML] From reproductive technologies to genome editing in small ruminants: An embryo's journey

A Menchaca, PC dos Santos-Neto, F Cuadro… - Animal …, 2018 - ncbi.nlm.nih.gov
The beginning of this century has witnessed great advances in the understanding of ovarian
physiology and embryo development, in the improvement of assisted reproductive …