Background Parecoxib plays an important role in inhibition of human cancer. However, the
effect of parecoxib on esophageal squamous cell carcinoma (ESCC) is still not well known …

Parecoxib, a well‐recognized nonsteroidal anti‐inflammatory drug, has been reported to
possess anticancer properties in various tumor types. In this work, we aimed to investigate …

Colorectal cancer is the third leading cause of cancer death in Taiwan. Current treatments
involve combination of surgical resection, radiation, and chemotherapy. These treatments …

AIMS: Combinatorial therapies that target multiple signaling pathways may provide
improved therapeutic responses over monotherapies. In the present study, we evaluated the …

Valdecoxib is a second generation selective COX-2 inhibitor that can induce cell apoptosis
in a variety of cell types, but its precise regulatory mechanism is unknown. Apoptosis of …

Celecoxib Inhibits Hepatocellular Carcinoma Cell Growth and Migration by Targeting PNO1 -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Gastric cancer, one of the most common malignancies worldwide, typically has a poor
prognosis and poor survival rate. Previous studies have investigated the chemopreventive …

Celecoxib inhibits proliferation and induces apoptosis in human tumors, but the molecular
mechanisms for these processes are poorly understood. In this study, we evaluated the …

Barrett's esophagus (BE) and esophageal adenocarcinoma (ADC) is associated with reflux
of duodenal contents. Cyclooxygenase (COX)-2 is over-expressed in BE and ADC, and …

Aim: To investigate the mechanisms underlying the anticancer effect of celecoxib on
nasopharyngeal carcinoma (NPC). Methods: NPC cell lines, HNE1 and CNE1-LMP1, were …