An asymmetric synthesis of Levetiracetam

V Raju, S Somaiah, S Sashikanth, E Laxminarayana… - 2014 - nopr.niscpr.res.in
An asymmetric synthesis of (S)-levetiracetam has been developed through application of a
Strecker reaction using [(1S)-1-(4-methoxyphenyl) ethyl] amine hydrochloride as a chiral …

A synthesis of levetiracetam based on (S)-N-phenylpantolactam as a chiral auxiliary

F Boschi, P Camps, M Comes-Franchini… - Tetrahedron …, 2005 - Elsevier
The synthesis of levetiracetam and its enantiomer by deracemization of (±)-2-bromobutyric
acid using either (S)-or (R)-N-phenylpantolactam as chiral auxiliaries, followed by SN2 …

Enantioselective Synthesis of Antiepileptic Drug: (‐)‐Levetiracetam—Synthetic Applications of the Versatile New Chiral N‐Sulfinimine

K Chandra Babu, R Buchi Reddy, E Naresh… - Journal of …, 2013 - Wiley Online Library
We report an asymmetric synthesis of (‐)‐Levetiracetam (1) in six steps starting from
versatile new chiral N‐sulfinimine (3). The key step, stereoselective 1, 2‐addition of …

An alternate synthesis of enantiomerically pure levetiracetam (Keppra®)

M Mujahid, P Mujumdar, M Sasikumar, SS Kunte… - Tetrahedron …, 2012 - Elsevier
An alternate synthesis of enantiomerically pure levetiracetam (Keppra®) - ScienceDirect Skip
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Total synthesis of levetiracetam

A Narczyk, M Mrozowicz, S Stecko - Organic & biomolecular chemistry, 2019 - pubs.rsc.org
Total synthesis of levetiracetam, an active ingredient of epilepsy treatment medications, is
reported. The reported method is based on a one-pot dehydration/sigmatropic …

Levetiracetam.

H Alrabiah - Profiles of Drug Substances, Excipients, and Related …, 2019 - europepmc.org
A comprehensive profile of levetiracetam is presented in this chapter which includes its
description, formula, elemental analysis, appearance, uses and applications. Different …

Novel crystalline forms of levetiracetam

R Parthasaradhi, R Rathanakar, R Raji… - US Patent App. 10 …, 2005 - Google Patents
US20050143445A1 - Novel crystalline forms of levetiracetam - Google Patents
US20050143445A1 - Novel crystalline forms of levetiracetam - Google Patents Novel …

Process for producing levetiracetam

BZ Dolitzky, J Hildesheim, S Finogueev - US Patent 7,132,552, 2006 - Google Patents
US7132552B2 - Process for producing levetiracetam - Google Patents US7132552B2 -
Process for producing levetiracetam - Google Patents Process for producing levetiracetam …

Sustained-release levetiracetam composition and preparation process

H Brochart, E Foucher - US Patent App. 12/525,920, 2010 - Google Patents
A subject of the present invention is a novel formulation of levetiracetam making it possible
to obtain a solid pharmaceutical composition, particularly intended for oral administration, for …

Levetiracetam.

M Carreno - Drugs of Today (Barcelona, Spain: 1998), 2007 - europepmc.org
Levetiracetam (LEV) is a broad-spectrum antiepileptic drug that is effective against a variety
of seizure types. It is a pyrridoline derivative with a very favourable pharmacokinetic profile …