Codon usage bias refers to the phenomenon where specific codons are used more often
than other synonymous codons during translation of genes, the extent of which varies within …

Background Codon bias is a phenomenon of non-uniform usage of codons whereas codon
context generally refers to sequential pair of codons in a gene. Although genome …

Selection on codon usage bias is well documented in a number of microorganisms. Whether
codon usage is also generally shaped by natural selection in large organisms, despite their …

Background It is widely acknowledged that synonymous codons are used unevenly among
genes in a genome. In organisms under translational selection, genes encoding highly …

Background Synonymous codon usage bias (SCUB) is an inevitable phenomenon in
organismic taxa, generally referring to differences in the occurrence frequency of codons …

Codon usage bias is the preferential or non-random use of synonymous codons, a
ubiquitous phenomenon observed in bacteria, plants and animals. Different species have …

Synonymous codon usage biases are associated with various biological factors, such as
gene expression level, gene length, gene translation initiation signal, protein amino acid …

In a wide variety of organisms, synonymous codons are used with different frequencies, a
phenomenon known as codon bias. Population genetic studies have shown that …

The phenomenon of codon usage bias has been important in the study of evolution because
it provides examples of weak selection working at the molecular level. During the last two …

Since the genetic code is degenerate, several codons are translated to the same amino
acid. Although these triplets were historically considered to be “synonymous” and therefore …