Abstract Benzo [a] pyrene (BaP) exposure has been associated with an increased risk of
carcinogenesis. We investigated the effects of BaP on cell viability, the promoter methylation …

In the US alone, around 60,000 lives/year are lost to colon cancer. In order to study the
mechanisms of colon carcinogenesis, in vitro model systems are required in addition to in …

Exposures to environmental carcinogens and unhealthy lifestyle choices increase the
incidence of breast cancer. One such compound, benzo (a) pyrene (BaP), leads to covalent …

Abstract Background Benzo [a] pyrene (BaP) is a widespread environmental genotoxic
carcinogen that damages DNA by forming adducts. This damage along with activation of the …

Abstract Benzo (a) pyrene (BaP), the earliest and most significant carcinogen among
polycyclic aromatic hydrocarbons (PAHs), has been found in foods, tobacco smoke, and …

Human colon carcinoma cells (HCT116) differing in p53 status were exposed to benzo (a)
pyrene (BaP) or anti-benzo (a) pyrene-trans-7, 8-dihydrodiol-9, 10-epoxide (BPDE) and their …

Abstract Benzo [a] pyrene (BaP) is one of the most thoroughly studied polycyclic aromatic
hydrocarbons (PAHs) and a widespread organic pollutant in various areas of human life. Its …

Background The multi-step process of carcinogenesis can be more fully understood by
characterizing gene expression changes induced in cells by carcinogens. In this study …

Benzo [a] pyrene (BaP) is cytotoxic and/or genotoxic to lung, stomach and skin tissue in the
body. However, the effect of BaP on cervical tissue remains unclear. The present study …

Bisphenol A (BPA), an estrogenic endocrine disruptor, is widely used in the production of
polycarbonate plastic and epoxy resins, resulting in high risk on human health. In present …