A randomized phase III study comparing dacarbazine, BCNU, cisplatin and tamoxifen with dacarbazine and interferon in advanced melanoma
MR Middleton, P Lorigan, J Owen, L Ashcroft… - British journal of …, 2000 - nature.com
The purpose of this study was to compare the response rate, overall and 1-year survival in
patients with advanced melanoma treated with a standard therapy, dacarbazine and …
patients with advanced melanoma treated with a standard therapy, dacarbazine and …
Phase II study of second-line therapy with DTIC, BCNU, cisplatin and tamoxifen (Dartmouth regimen) chemotherapy in patients with malignant melanoma previously …
DJ Propper, JP Braybrooke, NC Levitt… - British journal of …, 2000 - nature.com
This study assessed response rates to combination dacarbazine (DTIC), BCNU
(carmustine), cisplatin and tamoxifen (DBPT) chemotherapy in patients with progressive …
(carmustine), cisplatin and tamoxifen (DBPT) chemotherapy in patients with progressive …
Phase II randomized study of dacarbazine, carmustine, cisplatin and tamoxifen versus dacarbazine alone in advanced melanoma patients
VC Sileni, R Nortilli, SML Aversa… - Melanoma …, 2001 - journals.lww.com
This randomized phase II trial was performed to define the activity and toxicity of the
combination of dacarbazine (DTIC), carmustine (BCNU), cisplatin (DDP) and tamoxifen …
combination of dacarbazine (DTIC), carmustine (BCNU), cisplatin (DDP) and tamoxifen …
Phase III trial of dacarbazine versus dacarbazine with interferon alpha-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon alpha-2b and …
CI Falkson, J Ibrahim, JM Kirkwood… - Journal of Clinical …, 1998 - ascopubs.org
PURPOSE To investigate the response rate, time to treatment failure (TTF), overall survival,
and toxicity in patients with metastatic melanoma treated with dacarbazine alone …
and toxicity in patients with metastatic melanoma treated with dacarbazine alone …
Prospective randomized comparison of dacarbazine (DTIC) versus DTIC plus interferon-alpha (IFN-α) in metastatic melanoma
AM Young, J Marsden, A Goodman, A Burton, JA Dunn - Clinical Oncology, 2001 - Elsevier
Dacarbazine (DTIC) has been the mainstay of chemotherapy for metastatic melanoma for
over two decades, but only 15%–20% of patients respond and benefit is usually transient …
over two decades, but only 15%–20% of patients respond and benefit is usually transient …
Experience with interferon alpha 2b combined with dacarbazine in the treatment of metastatic malignant melanoma
CI Falkson - Medical Oncology, 1995 - Springer
A prospectively randomized trial was undertaken to compare dacarbazine (DTIC) alone with
DTIC plus interferon in patients with metastatic malignant melanoma. Of the 73 patients who …
DTIC plus interferon in patients with metastatic malignant melanoma. Of the 73 patients who …
Randomized phase II trial of BCDT [carmustine (BCNU), cisplatin, dacarbazine (DTIC) and tamoxifen] with or without interferon alpha (IFN-α) and interleukin (IL-2) in …
SR Johnston, DO Constenla, J Moore… - British journal of …, 1998 - nature.com
The purpose of this study was to evaluate in a randomized phase II trial the efficacy and
toxicity of combination biochemotherapy compared with chemotherapy alone in patients with …
toxicity of combination biochemotherapy compared with chemotherapy alone in patients with …
Randomized trial of dacarbazine versus bleomycin, vincristine, lomustine and dacarbazine (BOLD) chemotherapy combined with natural or recombinant interferon-α …
MS Vuoristo, M Hahka-Kemppinen… - Melanoma …, 2005 - journals.lww.com
This randomized phase II study was designed to compare the efficacy and tolerability of
dacarbazine (DTIC) and bleomycin, vincristine, lomustine and DTIC (BOLD) combined with …
dacarbazine (DTIC) and bleomycin, vincristine, lomustine and DTIC (BOLD) combined with …
A phase II study of dacarbazine, cisplatin, interferon-α and high-dose interleukin-2 in 'poor-risk'metastatic melanoma
TM Proebstle, C Scheibenbogen, W Sterry… - European Journal of …, 1996 - Elsevier
Melanoma patients with very advanced disease have usually not been included in chemo-
immunotherapy trials. We report on 22 melanoma patients, including 5 with reduced …
immunotherapy trials. We report on 22 melanoma patients, including 5 with reduced …
Interferon-alpha 2a does not improve response or survival when combined with dacarbazine in metastatic malignant melanoma: results of a multi-institutional …
DB Thomson, M Adena, GR McLeod, P Hersey… - Melanoma …, 1993 - europepmc.org
Following extensive phase II trials of the combination of dacarbazine and interferon-alpha
2a we performed a prospective, randomized, controlled trial of this combination versus …
2a we performed a prospective, randomized, controlled trial of this combination versus …