Background Glioblastomas are lethal brain tumors under the current combinatorial
therapeutic strategy that includes surgery, chemo-and radio-therapies. Extensive changes in …

Recurrent glioblastomas are frequently found near subventricular zone (SVZ) areas of the
brain where neural stem cells (NSCs) reside, and glioblastoma-derived extracellular …

Objective Glioma is one of the most prevalently diagnosed types of primary malignant brain
tumors. Glioma stem cells (GSCs) are crucial in glioma recurrence. This study aims to …

Neural stem/progenitor cells (NPCs) are known to have potent therapeutic effects in
neurological disorders through the secretion of extracellular vesicles (EVs). Despite the …

Glioblastomas (GBM) are highly aggressive primary brain tumors. Complex and dynamic
tumor microenvironment (TME) plays a crucial role in the sustained growth, proliferation, and …

Diffuse gliomas are lethal tumors of the central nervous system (CNS) characterized by
infiltrative growth, aggressive nature, and therapeutic resistance. The recent 2016 WHO …

We have previously uncovered the impact of oncogenic and differentiation processes on
extracellular vesicles (EVs) in cancer. This is of interested in the context of glioma stem cells …

Glioblastoma (GBM) is the most common primary malignant brain tumor and despite optimal
treatment, long‐term survival remains uncommon. GBM can be roughly divided into three …

Glioblastoma is the most aggressive brain tumour with short survival, partly due to resistance
to conventional therapy. Glioma stem cells (GSC) are likely to be involved in treatment …

The perivascular niche in glioma is critical for the maintenance of glioma stem cells (GSCs),
and tumour-endothelial cell (EC) communication impacts tumourigenesis in ways that are …